The recent development of commercial panel-based molecular diagnostics for the rapid
detection of pathogens in positive blood culture bottles, respiratory specimens, stool, and …

The universal immunization of infants and toddlers with pneumococcal conjugate vaccine
(PCV) in the United States beginning in 2000 heralded a new era for pneumococcal disease …

Enterobacteriaceae are a common source of both community-and hospital-acquired
infections. The resistance of Enterobacteriaceae to β-lactam antibiotics is a major public …

The number of patients at risk of suffering invasive fungal infection (IFI) is increasing.
Because of its high mortality, new rapid and accurate diagnostic tools are needed. Last …

Introduction: The rapid detection of resistance is a challenge for clinical microbiologists who
wish to prevent deleterious individual and collective consequences such as (i) delaying …

There are several approaches available for purifying microorganisms prior to matrix-assisted
laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) analysis. In …

Objectives Conventional microbiological procedures for the isolation of bacteria from
biological fluids consist of culture on solid media and enrichment broth. However, these …

MS applications in microbiology have increased significantly in the past 10 years, due in part
to the proliferation of regulator‐approved commercial MALDI MS platforms for rapid …

Rapid and accurate identification and classification of microorganisms is of paramount
importance to public health and safety. With the advance of mass spectrometry (MS) …

As 16S ribosomal RNA (rRNA)-targeted sequencing can detect DNA from non-viable
bacteria, it can be used to identify pathogens from clinical samples even in patients …