The Ehrlich Pathway for Fusel Alcohol Production: a Century of Research on Saccharomyces cerevisiae Metabolism
LA Hazelwood, JM Daran, AJA Van Maris… - Applied and …, 2008 - Am Soc Microbiol
Saccharomyces cerevisiae has been used for at least eight millennia in the production of
alcoholic beverages (41). Along with ethanol and carbon dioxide, fermenting cultures of this …
alcoholic beverages (41). Along with ethanol and carbon dioxide, fermenting cultures of this …
Stoichiometry and compartmentation of NADH metabolism in Saccharomyces cerevisiae
BM Bakker, KM Overkamp… - FEMS microbiology …, 2001 - academic.oup.com
In Saccharomyces cerevisiae, reduction of NAD+ to NADH occurs in dissimilatory as well as
in assimilatory reactions. This review discusses mechanisms for reoxidation of NADH in this …
in assimilatory reactions. This review discusses mechanisms for reoxidation of NADH in this …
[HTML][HTML] Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0
Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration
of the relation between genotype and phenotype. Streamlined integration of enzyme …
of the relation between genotype and phenotype. Streamlined integration of enzyme …
Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network
J Förster, I Famili, P Fu, BØ Palsson… - Genome research, 2003 - genome.cshlp.org
The metabolic network in the yeast Saccharomyces cerevisiae was reconstructed using
currently available genomic, biochemical, and physiological information. The metabolic …
currently available genomic, biochemical, and physiological information. The metabolic …
Redox control and oxidative stress in yeast cells
E Herrero, J Ros, G Bellí, E Cabiscol - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
Protein structure and function can be altered by reactive oxygen species produced either by
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …
cell metabolism or by external oxidants. Although catalases, superoxide dismutases and …
[HTML][HTML] Evolutionary programming as a platform for in silico metabolic engineering
Background Through genetic engineering it is possible to introduce targeted genetic
changes and hereby engineer the metabolism of microbial cells with the objective to obtain …
changes and hereby engineer the metabolism of microbial cells with the objective to obtain …
Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae
GN Vemuri, MA Eiteman, JE McEwen… - Proceedings of the …, 2007 - National Acad Sciences
Respiratory metabolism plays an important role in energy production in the form of ATP in all
aerobically growing cells. However, a limitation in respiratory capacity results in overflow …
aerobically growing cells. However, a limitation in respiratory capacity results in overflow …
Structure and organization of mitochondrial respiratory complexes: a new understanding of an old subject
G Lenaz, ML Genova - Antioxidants & redox signaling, 2010 - liebertpub.com
The enzymatic complexes of the mitochondrial respiratory chain have been extensively
investigated in their structural and functional properties. A clear distinction is possible today …
investigated in their structural and functional properties. A clear distinction is possible today …
The alcohol dehydrogenases of Saccharomyces cerevisiae: a comprehensive review
O De Smidt, JC Du Preez, J Albertyn - FEMS yeast research, 2008 - academic.oup.com
Alcohol dehydrogenases (ADHs) constitute a large family of enzymes responsible for the
reversible oxidation of alcohols to aldehydes with the concomitant reduction of NAD+ or …
reversible oxidation of alcohols to aldehydes with the concomitant reduction of NAD+ or …
Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network
I Famili, J Förster, J Nielsen… - Proceedings of the …, 2003 - National Acad Sciences
Full genome sequences of prokaryotic organisms have led to reconstruction of genome-
scale metabolic networks and in silico computation of their integrated functions. The first …
scale metabolic networks and in silico computation of their integrated functions. The first …