2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of …
B Williams, G Mancia, W Spiering… - European heart …, 2018 - academic.oup.com
Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …
Cardiac innervation and sudden cardiac death
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …
Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham …
Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …
Endovascular ultrasound renal denervation to treat hypertension (RADIANCE-HTN SOLO): a multicentre, international, single-blind, randomised, sham-controlled trial
Background Early studies suggest that radiofrequency-based renal denervation reduces
blood pressure in patients with moderate hypertension. We investigated whether an …
blood pressure in patients with moderate hypertension. We investigated whether an …
[PDF][PDF] Guía ESC/ESH 2018 sobre el diagnóstico y tratamiento de la hipertensión arterial
La tarea de elaboración de GPC incluye la creación de herramientas educativas y
programas de implementación de las recomendaciones. Para su implementación, se …
programas de implementación de las recomendaciones. Para su implementación, se …
Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry
F Mahfoud, M Böhm, R Schmieder… - European Heart …, 2019 - academic.oup.com
Aims Several studies and registries have demonstrated sustained reductions in blood
pressure (BP) after renal denervation (RDN). The long-term safety and efficacy after RDN in …
pressure (BP) after renal denervation (RDN). The long-term safety and efficacy after RDN in …
Predictors of blood pressure response in the SYMPLICITY HTN-3 trial
DE Kandzari, DL Bhatt, S Brar… - European heart …, 2015 - academic.oup.com
Abstract Aims The SYMPLICITY HTN-3 randomized, blinded, sham-controlled trial confirmed
the safety of renal denervation (RDN), but did not meet its primary efficacy endpoint. Prior …
the safety of renal denervation (RDN), but did not meet its primary efficacy endpoint. Prior …
Optimum and stepped care standardised antihypertensive treatment with or without renal denervation for resistant hypertension (DENERHTN): a multicentre, open …
Background Conflicting blood pressure-lowering effects of catheter-based renal artery
denervation have been reported in patients with resistant hypertension. We compared the …
denervation have been reported in patients with resistant hypertension. We compared the …
Anatomic assessment of sympathetic peri-arterial renal nerves in man
K Sakakura, E Ladich, Q Cheng, F Otsuka… - Journal of the American …, 2014 - jacc.org
Background: Although renal sympathetic denervation therapy has shown promising results
in patients with resistant hypertension, the human anatomy of peri-arterial renal nerves is …
in patients with resistant hypertension, the human anatomy of peri-arterial renal nerves is …
A call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on …
Executive summary Elevated blood pressure is the strongest modifiable risk factor for
cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as …
cardiovascular disease worldwide. Despite extensive knowledge about ways to prevent as …