Chronopathophysiological implications of orexin in sleep disturbances and lifestyle-related disorders

H Tsuneki, T Wada, T Sasaoka - Pharmacology & therapeutics, 2018 - Elsevier
Sleep, a mysterious behavior, has recently been recognized as a crucial factor for health
and longevity. The daily sleep/wake cycle provides the basis of biorhythms controlling whole …

Sleep and orexin: A new paradigm for understanding behavioural-variant frontotemporal dementia?

YT Hwang, O Piguet, JR Hodges, R Grunstein… - Sleep Medicine …, 2020 - Elsevier
Behavioural variant frontotemporal dementia (bvFTD) is a complex and heterogeneous
disorder with as yet unidentified unifying pathophysiological mechanism. There is emerging …

Sleep disturbances in anorexia nervosa subtypes in adolescence

F Bat-Pitault, C Da Silva, I Charvin… - Eating and Weight …, 2021 - Springer
Purpose This retrospective study investigated, for the first time, sleep characteristics in
anorexia nervosa (AN) subtypes and the clinical profile in adolescents, as well as the quality …

Effects of sleep quality on non-alcoholic fatty liver disease: a cross-sectional survey

A Takahashi, Y Anzai, M Kuroda, M Kokubun… - BMJ open, 2020 - bmjopen.bmj.com
Background The effects of sleep quality on the risk of developing non-alcoholic fatty liver
disease (NAFLD) remain uncertain. The purpose of this study was to clarify the association …

Reduced plasma orexin-A concentrations are associated with cognitive deficits in anorexia nervosa

T Steward, G Mestre-Bach, R Granero, I Sánchez… - Scientific reports, 2019 - nature.com
Orexins/hypocretins are neuropeptides implicated in numerous processes, including food
intake and cognition. The role of these peptides in the psychopathology of anorexia nervosa …

The moderating role of sleep duration on momentary relations between negative affect and loss‐of‐control eating in children and adolescents

SM Manasse, AA Haedt‐Matt, KE Smith… - European Eating …, 2022 - Wiley Online Library
Objective Loss‐of‐control (LOC) eating is associated with eating disorders and obesity, and
thus it is imperative to understand its momentary risk factors in order to improve intervention …

Sleep quality in patients with chronic spontaneous urticaria and relation with Orexin-A, leptin, and ghrelin

S Gultuna, B Basa Akdogan, M Gonul… - Allergy and Asthma …, 2024 - ingentaconnect.com
Background: Sleep can be affected in patients with chronic spontaneous urticaria (CSU).
The mechanisms of sleep regulation remain poorly understood. Orexin-A, a neuroexcitatory …

A higher body mass index in Chinese inpatients with chronic schizophrenia is associated with elevated plasma orexin-A levels and fewer negative symptoms

Z Liu, Y Zhang, T Zhao, J Wang, L Xia… - Nordic Journal of …, 2020 - Taylor & Francis
Objective: Orexin-A is involved in numerous physiological functions, such as feeding
behavior and energy balance. Yet, the associations among the orexin system, weight …

The association between serum orexin-A levels and sleep quality in pregnant women

L Qin, Y Luo, H Chang, H Zhang, Z Zhu, Y Du, K Liu… - Sleep Medicine, 2023 - Elsevier
Objective/background Orexin has been shown to regulate the sleep-wake cycle, and it may
play a major role in the pathogenesis of sleep disorders; however, its role in sleep disorders …

Subjective sleep disorders and daytime sleepiness in patients with restrictive type anorexia nervosa and effects on quality of life: a case–control study

A Romigi, NB Mercuri, M Caccamo, F Testa… - Sleep and Biological …, 2022 - Springer
To evaluate sleep disorders and daytime drowsiness in a cohort of patients affected by
anorexia nervosa and their impact on health-related quality of life. We evaluated patients …