The most frequent adult-type primary CNS tumours are diffuse gliomas, but a large variety of
rarer CNS tumour types exists. The classification of these tumours is increasingly based on …

Summary The European Association for Neuro-Oncology guideline provides
recommendations for the clinical care of adult patients with astrocytic and oligodendroglial …

Background Isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas are malignant brain
tumors that cause considerable disability and premature death. Vorasidenib, an oral brain …

Isocitrate dehydrogenase (IDH) mutant gliomas are the most common adult, malignant
primary brain tumors diagnosed in patients younger than 50, constituting an important cause …

Although meningiomas are the most common intracranial tumours, the level of evidence to
provide recommendations for the diagnosis and treatment of meningiomas is low compared …

Background Outcome of low-grade glioma (WHO grade II) is highly variable, reflecting
molecular heterogeneity of the disease. We compared two different, single-modality …

Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …

Gliomas are primary brain tumours that are thought to derive from neuroglial stem or
progenitor cells. On the basis of their histological appearance, they have been traditionally …

Purpose Anaplastic oligodendroglioma are chemotherapy-sensitive tumors. We now present
the long-term follow-up findings of a randomized phase III study on the addition of six cycles …

Background Radiotherapy is the standard care in elderly patients with malignant
astrocytoma and the role of primary chemotherapy is poorly defined. We did a randomised …