In this narrative review, the biological/biochemical impact (toxicity) of a large array of known
individual uremic retention solutes and groups of solutes is summarized. We classified these …

The intestinal microbiota metabolic activity towards the available substrates generates
myriad bacterial metabolites that may accumulate in the luminal fluid. Among them, indole …

Chronic kidney disease (CKD) is associated with a high prevalence of cardiovascular
diseases. During CKD, the uremic toxin indoxyl sulfate (IS)—derived from tryptophan …

Chronic kidney disease (CKD) is characterized by the retention of a myriad of solutes termed
uraemic (or uremic) toxins, which inflict damage to several organs, including the …

Aims Precision microbiome modulation as a novel treatment strategy is a rapidly evolving
and sought goal. The aim of this study is to determine relationships among systemic gut …

Chronic kidney disease has a graded and independent inverse impact on cerebrovascular
health. Both thrombotic and hemorrhagic complications are highly prevalent in chronic …

Patients with chronic kidney disease (CKD) display an elevated risk of thrombosis.
Thrombosis occurs in cardiovascular events, such as venous thromboembolism, stroke, and …

Background Patients with CKD are at high risk for thrombotic and hemorrhagic
complications. Abnormalities in platelet function are central to these complications, but …

Chronic kidney disease (CKD) is deemed to be a worldwide health concern connected with
neurological manifestations. The etiology of central nervous system (CNS) disorders in CKD …

Kidney disease is a major global health concern, affecting millions of people. Nephrologists
have shown interest in platelets because of coagulation disorders caused by renal diseases …