The decline in the fisheries of traditional marine species has been an incentive for the
diversification of today's aquaculture sector into the intensive rearing of many finfish species …

For decades immunologists have relied heavily on the mouse model for their experimental
designs. With the realization of the important role innate immunity plays in orchestrating …

Interferons (IFNs) are secreted proteins, which induce vertebrate cells into an antiviral state.
In mammals, three families of IFNs (type I IFN, type II IFN and IFN-λ) can be distinguished on …

Interferon (IFN) response is the first line of host defense against virus infection. The recent
years have witnessed tremendous progress in understanding of fish IFN antiviral response …

The zebrafish, Danio rerio, has come to the forefront of biomedical research as a powerful
model for the study of development, neurobiology, and genetics of humans. In recent years …

The amenability of the zebrafish to in vivo imaging and genetic analysis has fueled
expanded use of this vertebrate model to investigate the molecular and cellular foundations …

The zebrafish (Danio rerio) is a widely used model for developmental biology, neurobiology,
toxicology, and genetic disease. Recently, the zebrafish has been recognized as a valuable …

Mammalian immune responses to LPS exposure are typified by the robust induction of NF-
κB and IFN-β responses largely mediated by TLR4 signal transduction pathways. In contrast …

Arsenic has been associated with a multitude of human health problems; however, its impact
on host resistance to infection has not been extensively researched. In vertebrates, the …

The purpose of this chapter is to provide readers with a general overview of the fish immune
system, including commonalities and particularities in comparison with higher vertebrate …