Recent advances and challenges of the drugs acting on monoamine transporters

W Xue, T Fu, G Zheng, G Tu, Y Zhang… - Current medicinal …, 2020 - ingentaconnect.com
Background: The human Monoamine Transporters (hMATs), primarily including hSERT,
hNET and hDAT, are important targets for the treatment of depression and other behavioral …

[HTML][HTML] The story of clobenpropit and CXCR4: can be an effective drug in cancer and autoimmune diseases?

M Abbasifard, K Bagherzadeh… - Frontiers in …, 2024 - frontiersin.org
Clobenpropit is a histamine H3 receptor antagonist and has developed as a potential
therapeutic drug due to its ability to inhibit CXCR4, a chemokine receptor involved in …

[HTML][HTML] Milligram scale enantioresolution of promethazine and its main metabolites, determination of their absolute configuration and assessment of enantioselective …

MM Coelho, I Costa, ACF de Albuquerque… - … of Pharmaceutical and …, 2024 - Elsevier
The misuse of pharmaceuticals has significantly increased in recent decades, becoming a
major public health concern. The risks associated with medication misuse are particularly …

Histamine H3 receptor activation reduces the impairment in prepulse inhibition (PPI) of the acoustic startle response and Akt phosphorylation induced by MK-801 …

G Aquino-Miranda, N Rivera-Ramírez… - Progress in Neuro …, 2019 - Elsevier
We have investigated the effect of the local activation of histamine H 3 receptors (H 3 Rs) in
the rat prefrontal cortex (PFCx) on the impairment of pre-pulse inhibition (PPI) of the startle …

[HTML][HTML] Evaluation of 6-hydroxydopamine and rotenone in vitro neurotoxicity on differentiated SH-SY5Y cells using applied computational statistics

RF Simões, PJ Oliveira, T Cunha-Oliveira… - International Journal of …, 2022 - mdpi.com
With the increase in life expectancy and consequent aging of the world's population, the
prevalence of many neurodegenerative diseases is increasing, without concomitant …

Persistencia de impulsividad en adolescente con Trastorno Límite de Personalidad

A Rangel - Ciencia e Innovación en Salud, 2021 - revistas.unisimon.edu.co
Adolescence is a period of transition and changes where borderline personality traits can
influence the manifestations of a depressive illness. Adolescents may present dysphoric …

[HTML][HTML] Metabolite profiling fraksi-fraksi buah Jambu Wer (Prunus persica L. Batsch) menggunakan UPLC-QToF-MS/MS

RO Adsari - 2019 - etheses.uin-malang.ac.id
ENGLISH: Guava wer (Prunus persica L. Batsch) is a plant from the Tengger tribe which is
based on ethnopharmaceutical studies as an antidiarrheal, so it has the potential to be …