Metastasis remains a pivotal characteristic of cancer and is the primary contributor to cancer-
associated mortality. Despite its significance, the mechanisms governing metastasis are not …

The intricate interplay between the human immune system and cancer development
underscores the central role of immunotherapy in cancer treatment. Within this landscape …

Strategies to enhance the anti-tumor immune response of stereotactic ablative radiotherapy
(SABR) at primary tumors and abscopal sites are under intensive investigation. Here we …

Distant metastasis is responsible for high mortality in most cancer cases and the lung is one
of the most common target organs, severely affecting the quality of daily life and overall …

Cancer stem cells are the key link between malignant tumor progression and drug
resistance. This cell population has special properties that are different from those of …

Adaptive anti-tumor immunity is currently dependent on the natural immune system of the
body. The emergence of tumor immunotherapy has improved prognosis and prolonged the …

Immune cell migration is required for the development of an effective and robust immune
response. This elegant process is regulated by both cellular and environmental factors, with …

In the tumor microenvironment (TME), myeloid cells play a pivotal role. Myeloid-derived
immunosuppressive cells, including tumor-associated macrophages (TAMs) and myeloid …

The phenomenon of bone metastases presents a significant challenge within the context of
advanced cancer treatments, particularly pertaining to breast, prostate, and lung cancers …

Oxidative stress is characterized by the deregulation of the redox state in the cells, which
plays a role in the initiation of various types of cancers. The activity of galectin-1 (Gal-1) …