Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

Pyroptosis is a form of programmed cell death mediated by gasdermin and is a product of
continuous cell expansion until the cytomembrane ruptures, resulting in the release of …

In recent years, immunotherapy represented by immune checkpoint inhibitors (ICIs) has led
to unprecedented breakthroughs in cancer treatment. However, the fact that many tumors …

Although zeolitic imidazolate framework‐8 (ZIF‐8) has been applied in various tumor
therapies, the intrinsic immunogenicity remains unclear. Here, we initiatively discover that …

Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

In recent decades, chemotherapies targeting apoptosis have emerged and demonstrated
remarkable achievements. However, emerging evidence has shown that chemoresistance is …

In recent years, cancer immunotherapy based on immune checkpoint inhibitors (ICIs) has
achieved considerable success in the clinic. However, ICIs are significantly limited by the …

Apoptosis has long been recognized as a mechanism that kills the cancer cells by cytotoxic
drugs. In recent years, studies have proved that pyroptosis can also shrink tumors and inhibit …

Pyroptosis refers to the process of gasdermin-mediated lytic programmed cell death (PCD)
characterized by the release of pro-inflammatory cytokines. Our knowledge of pyroptosis has …

Pyroptosis provides a new direction and broad prospects for cancer immunotherapy.
However, the development of a nanoplatform as a pyroptosis inducer is limited, and the …