Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

Segmentation is a fundamental feature of the vertebrate body plan. This metameric
organization is first implemented by somitogenesis in the early embryo, when paired …

The emergence of the three germ layers and the lineage-specific precursor cells
orchestrating organogenesis represent fundamental milestones during early embryonic …

The generation of the components that make up the embryonic body axis, such as the spinal
cord and vertebral column, takes place in an anterior-to-posterior (head-to-tail) direction …

Every animal grows from a single fertilized egg into an intricate network of cell types and
organ systems. This process is captured in a lineage tree: a diagram of every cell's ancestry …

Elucidating the developmental processes of organisms requires a comprehensive
understanding of cellular lineages in the spatial, temporal, and molecular domains. In this …

Regeneration requires mechanisms for producing a wide array of cell types. Neoblasts are
stem cells in the planarian Schmidtea mediterranea that undergo fate specification to …

The development of the vertebrate body axis relies on the activity of different populations of
axial progenitors, including neuromesodermal progenitors. Currently, the term …

During early development the vertebrate embryo elongates through a combination of tissue
shape change, growth and progenitor cell expansion across multiple regions of the body …

In classical descriptions of vertebrate development, the segregation of the three embryonic
germ layers completes by the end of gastrulation. Body formation then proceeds in a head to …