[HTML][HTML] Consequences of obesity on the sense of taste: taste buds as treatment targets?

K Rohde, I Schamarek… - Diabetes & metabolism …, 2020 - synapse.koreamed.org
Premature obesity-related mortality is caused by cardiovascular and pulmonary diseases,
type 2 diabetes mellitus, physical disabilities, osteoarthritis, and certain types of cancer …

The role of saliva in taste and food intake

LE Martin, VA Gutierrez, AM Torregrossa - Physiology & behavior, 2023 - Elsevier
Saliva is well-described in oral food processing, but its role in taste responsiveness remains
understudied. Taste stimuli must dissolve in saliva to reach their receptor targets. This allows …

Independent amylase gene copy number bursts correlate with dietary preferences in mammals

P Pajic, P Pavlidis, K Dean, L Neznanova, RA Romano… - Elife, 2019 - elifesciences.org
The amylase gene (AMY), which codes for a starch-digesting enzyme in animals, underwent
several gene copy number gains in humans (Perry et al., 2007), dogs (Axelsson et al …

A subset of broadly responsive Type III taste cells contribute to the detection of bitter, sweet and umami stimuli

D Dutta Banik, ED Benfey, LE Martin, KE Kay… - PLoS …, 2020 - journals.plos.org
Taste receptor cells use multiple signaling pathways to detect chemicals in potential food
items. These cells are functionally grouped into different types: Type I cells act as support …

Addition of chocolate milk to diet corresponds to protein concentration changes in human saliva

CR Crawford, CA Running - Physiology & Behavior, 2020 - Elsevier
Salivary proteins have the potential to alter oral sensory perception of foods. In rodents,
dietary polyphenol exposure increases salivary concentrations of polyphenol-binding …

Salivary protein profile and food intake: a dietary pattern analysis

T Louro, C Simões, W Lima, L Carreira… - Journal of Nutrition …, 2021 - Wiley Online Library
Saliva research has gained interest due to its potential as a source of biomarkers. One of the
factors inducing changes in saliva, in the short term, is food intake, and evidence exist about …

TRPM4 and PLCβ3 contribute to normal behavioral responses to an array of sweeteners and carbohydrates but PLCβ3 is not needed for taste-driven licking for …

V Ascencio Gutierrez, LE Martin… - Chemical …, 2024 - academic.oup.com
The peripheral taste system is more complex than previously thought. The novel taste-
signaling proteins TRPM4 and PLCβ3 appear to function in normal taste responding as part …

Regional variation of bitter taste and aftertaste in humans

MJ Higgins, JE Hayes - Chemical senses, 2019 - academic.oup.com
Despite widespread and persistent myths of a tongue map, all 5 prototypical taste qualities
are sensed over the entire tongue. However, modern psychophysical data also suggest …

Repeated exposure to epigallocatechin gallate solution or water alters bitterness intensity and salivary protein profile

LA Davis, CA Running - Physiology & behavior, 2021 - Elsevier
Polyphenols, bitter and astringent compounds present in many healthy foods, induce varied
sensory responses across individuals. These differences in liking and flavor intensity may be …

The evolution of neuroscience as a research field relevant to dentistry

K Iwata, BJ Sessle - Journal of Dental Research, 2019 - journals.sagepub.com
The field of neuroscience did not exist as such when the Journal of Dental Research was
founded 100 y ago. It has emerged as an important scientific field relevant to dentistry in …