Organelle‐specific mechanisms in crosstalk between apoptosis and ferroptosis
P Wu, X Zhang, D Duan, L Zhao - Oxidative Medicine and …, 2023 - Wiley Online Library
Apoptosis has been extensively studied, whereas ferroptosis is a newly discovered form of
regulated cell death that involves iron‐dependent accumulations of lipid hydroperoxides …
regulated cell death that involves iron‐dependent accumulations of lipid hydroperoxides …
Lysosomal membrane permeabilization as a cell death mechanism in cancer cells
A Serrano-Puebla, P Boya - Biochemical Society Transactions, 2018 - portlandpress.com
Lysosomes are acidic organelles that contain hydrolytic enzymes that mediate the
intracellular degradation of macromolecules. Damage of these organelles often results in …
intracellular degradation of macromolecules. Damage of these organelles often results in …
Curcumin induces crosstalk between autophagy and apoptosis mediated by calcium release from the endoplasmic reticulum, lysosomal destabilization and …
A Moustapha, PA Pérétout, NE Rainey, F Sureau… - Cell Death …, 2015 - nature.com
Curcumin, a major active component of turmeric (Curcuma longa, L.), has anticancer effects.
In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but …
In vitro studies suggest that curcumin inhibits cancer cell growth by activating apoptosis, but …
The HN protein of Newcastle disease virus induces cell apoptosis through the induction of lysosomal membrane permeabilization
Y Chen, S Zhu, T Liao, C Wang, J Han, Z Yang… - Plos …, 2024 - journals.plos.org
Lysosomes are acidic organelles that mediate the degradation and recycling of cellular
waste materials. Damage to lysosomes can cause lysosomal membrane permeabilization …
waste materials. Damage to lysosomes can cause lysosomal membrane permeabilization …
p53 regulates lysosomal membrane permeabilization as well as cytoprotective autophagy in response to DNA-damaging drugs
G Yamashita, N Takano, H Kazama, K Tsukahara… - Cell Death …, 2022 - nature.com
Lysosomes are single-membraned organelles that mediate the intracellular degradation of
macromolecules. Various stress can induce lysosomal membrane permeabilization (LMP) …
macromolecules. Various stress can induce lysosomal membrane permeabilization (LMP) …
The inhibition of death receptor mediated apoptosis through lysosome stabilization following internalization of carboxyfullerene nanoparticles
Cells undergo apoptosis through two major pathways, the extrinsic pathway (death receptor
pathway) and the intrinsic pathway (the mitochondrial pathway). It is well known that …
pathway) and the intrinsic pathway (the mitochondrial pathway). It is well known that …
Mechanisms of cellular effects directly induced by magnetic nanoparticles under magnetic fields
L Chen, C Chen, P Wang, T Song - Journal of nanomaterials, 2017 - Wiley Online Library
The interaction of magnetic nanoparticles (MNPs) with various magnetic fields could directly
induce cellular effects. Many scattered investigations have got involved in these cellular …
induce cellular effects. Many scattered investigations have got involved in these cellular …
In vitro and in vivo studies on potentiation of curcumin-induced lysosomal-dependent apoptosis upon silencing of cathepsin C in colorectal cancer cells
Cathepsins are lysosomal acid hydrolases that make crucial contributions to tumor
progression through a variety of signaling mechanisms, including autophagy, cell survival …
progression through a variety of signaling mechanisms, including autophagy, cell survival …
Phosphatidic acid mediates the targeting of tBid to induce lysosomal membrane permeabilization and apoptosis
Upon apoptotic stimuli, lysosomal proteases, including cathepsins and chymotrypsin, are
released into cytosol due to lysosomal membrane permeabilization (LMP), where they …
released into cytosol due to lysosomal membrane permeabilization (LMP), where they …
Europium-doped Gd2O3 nanotubes cause the necrosis of primary mouse bone marrow stromal cells through lysosome and mitochondrion damage
Y Jin, S Chen, J Duan, G Jia, J Zhang - Journal of inorganic biochemistry, 2015 - Elsevier
With the wide applications of europium-doped Gd 2 O 3 nanoparticles (Gd 2 O 3: Eu 3+ NPs)
in biomedical fields, it will inevitably increase the chance of human exposure. It was reported …
in biomedical fields, it will inevitably increase the chance of human exposure. It was reported …