Abstract α-Amino nitrile compounds have a profound impact on bio-chemical sciences, as
they have been prepared from inexpensive starting materials and have become valuable …

1. Introduction a-Aminophosphonic acids and their derivatives exhibit diverse biological
activities that are the basis of their important pharmacological applications. 1 Their …

A highly efficient one-pot three-component regioselective synthesis of 2-amino-3-cyano-4H-
chromene and tetrahydrobenzo [b] pyran derivatives has been developed by annulation of …

Research concerning green solvents is focused on reducing environmental damages due to
the use of toxic solvents in organic chemistry. Hence, there have been developed a lot of …

Hantzsch 1, 4-dihydropyridine, polyhydroquinoline and 1, 8-dioxodecahydroacridines
derivatives were synthesized in excellent yields in trifluoroethanol (TFE). The solvent (TFE) …

Trifluoroethanol (TFE) is found to be an efficient and recyclable medium in promoting one-
pot, four-component coupling reactions of aldehydes, ketones, malononitrile, and …

This report provides an overview of the practical methods for preparing symmetrically α, α-
disubstituted α-amino acids and their derivatives. Despite the growing application of this …

A simple and efficient method for the chemoselective N-Boc protection of the amine moiety
in a variety of compounds is described using di-tert-butyl dicarbonate and guanidine …

A convenient, environmentally friendly and efficient procedure for the synthesis 3, 4-dihydro-
1H-indazolo [1, 2-b] phthalazine-1, 6, 11 (2H, 13H)-trione derivatives has been developed …

A rapid and highly efficient method for the regioselective synthesis of thiophene derivatives
has been developed by annulation of β-ketothioamides with arylglyoxals and 5, 5-dimethyl …