Conventional Sanger sequencing has been the mainstay for DNA sequencing in the
research community, generating information for countless DNA fragments and whole …

Bioluminescence has been observed in nature since the dawn of time, but now, scientists
are harnessing it for analytical applications. Laura Rowe, Emre Dikici, and Sylvia Daunert of …

The results of investigations into performing DNA sequencing chemistry on a picoliter‐scale
electrowetting digital microfluidic platform are reported. Pyrosequencing utilizes …

An integrated microdevice was utilized for the autonomous coupling of solid-phase
extraction (SPE) to micellar electrokinetic chromatography (MEKC). Porous plugs of …

This review describes recently emerging optical and microfluidic technologies suitable for
point-of-care genetic analysis systems. Such systems must rapidly detect hundreds of …

Polymerase chain reaction primers and methods directed to detecting the EGFR mutant C->
T at the position correspond ing to base 2369 of EGFR cDNA. The invention provides a PCR …

In this work, we measured the primer extension kinetics of the Klenow fragment (exo-) to
achieve rapid detection of single nucleotide polymorphism (SNP). Both the matching and the …

Ecotilling is a high-throughput method of discovery and analysis of single-nucleotide
polymorphism (SNP) variations in natural populations, but it requires a substantial …

In the past few years, electrophoresis microchips have been increasingly utilized to
interrogate genetic variations in the human and other genomes. Microfluidic devices can be …

Pyrosequencing is a highly effective method for quantitatively genotyping short genetic
sequences, but it currently is hampered by a labor-intensive sample preparation process …