The need for better antifungal therapy is commonly accepted in view of the high mortality
rates associated with systemic infections, the low number of available antifungal classes …

Dimorphic fungi cause several endemic mycoses which range from subclinical respiratory
infections to life-threatening systemic disease. Pathogenic-phase cells of Histoplasma …

Aim The aim of this present study was to investigate the antifungal mechanism of sertraline
against Candida auris (C. auris) and its effect on biofilm formation. Methods and Results …

Cryptococcus spp. are common opportunistic fungal pathogens, particularly in HIV patients.
The approved drug miltefosine (MFS) has potential as an alternative antifungal against …

This study aimed to evaluate the in vitro antifungal activity of terpinen-4-ol, tyrosol, and β-
lapachone against strains of Coccidioides posadasii in filamentous phase (n= 22) and …

Standardized methodologies for determining the antifungal susceptibility of fungal
pathogens is central to the clinical management of invasive fungal disease. Yeast-form fungi …

Histoplasma capsulatum is a fungus that causes histoplasmosis. The increased evolution of
microbial resistance and the adverse effects of current antifungals help new drugs to …

This study investigated potential mechanisms of azole resistance among Candida albicans
from animals, including efflux pump activity, ergosterol content and gene expression. For this …

This study aimed to investigate the influence of tetraconazole and malathion, both used in
agricultural activities, on resistance to fluconazole, itraconazole and voriconazole in …

Aims This study aimed to evaluate the in vitro activity of miltefosine and levamisole against
strains of Coccidioides posadasii in the filamentous phase and strains of Histoplasma …