The Wnt/β-catenin signaling pathway plays important roles in embryonic development and
tissue homeostasis. Wnt signaling is induced, and β-catenin is activated, associated with the …

Diabetic nephropathy (DN) is a serious kidney-related complication of both type 1 and type 2
diabetes mellitus (T1DM, T2DM) and the second major cause of end-stage kidney disease …

Chronic kidney disease (CKD) is a major worldwide public health problem. The increase in
the number of patients with CKD and end-stage kidney disease requesting renal dialysis or …

As part of the glomerular filtration membrane, podocyte is terminally differentiated,
structurally unique, and highly specialized in maintaining kidney function. Proteinuria …

The increased incidence of membranous nephropathy (MN) has made it the most common
pathological type of primary nephrotic syndrome in adults in China. According to the theory …

Context Jiedutongluotiaogan formula (JTTF), a traditional Chinese medicine (TCM), could
promote islet function. However, the potential effect of JTTF on endoplasmic reticulum stress …

Background: Accumulating evidence suggests that traditional Chinese medicine (TCM) has
significant effects on reducing 24-h urinary protein (24-h UPRO) and improves renal function …

In idiopathic membranous nephropathy, the complement membrane attack complex, more
commonly referred to as complement 5b‑9 (C5b‑9), induces glomerular epithelial cell injury …

Podocytes form a key component of the glomerular filtration barrier. Damage to podocytes is
referred to as “podocyte disease.” There are many causes of podocyte injury, including …