Inverse opal scaffolds and their biomedical applications

YS Zhang, C Zhu, Y Xia - Advanced Materials, 2017 - Wiley Online Library
Three‐dimensional porous scaffolds play a pivotal role in tissue engineering and
regenerative medicine by functioning as biomimetic substrates to manipulate cellular …

Cell-seeded biomaterial scaffolds: the urgent need for unanswered accelerated angiogenesis

H Shokrani, A Shokrani, SM Sajadi, F Seidi… - International journal …, 2022 - Taylor & Francis
One of the most arduous challenges in tissue engineering is neovascularization, without
which there is a lack of nutrients delivered to a target tissue. Angiogenesis should be …

Fast-degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neoartery

W Wu, RA Allen, Y Wang - Nature medicine, 2012 - nature.com
Host remodeling is important for the success of medical implants, including vascular
substitutes. Synthetic and tissue-engineered grafts have yet to show clinical effectiveness in …

Combining electrospinning and fused deposition modeling for the fabrication of a hybrid vascular graft

M Centola, A Rainer, C Spadaccio… - …, 2010 - iopscience.iop.org
Tissue engineering of blood vessels is a promising strategy in regenerative medicine with a
broad spectrum of potential applications. However, many hurdles for tissue-engineered …

Angiogenic biomaterials to promote therapeutic regeneration and investigate disease progression

MT Ngo, BAC Harley - Biomaterials, 2020 - Elsevier
The vasculature is a key component of the tissue microenvironment. Traditionally known for
its role in providing nutrients and oxygen to surrounding cells, the vasculature is now also …

Progressive reinvention or destination lost? Half a century of cardiovascular tissue engineering

P Zilla, M Deutsch, D Bezuidenhout… - Frontiers in …, 2020 - frontiersin.org
The concept of tissue engineering evolved long before the phrase was forged, driven by the
thromboembolic complications associated with the early total artificial heart programs of the …

Smart and biostable polyurethanes for long-term implants

S Kim, S Liu - ACS Biomaterials Science & Engineering, 2018 - ACS Publications
This article reviews stimuli-responsive and biostable polyurethanes (PUs) and discusses
biomedical applications of smart PUs with a particular focus on long-term implantable PU …

The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models

T Pennel, G Fercana, D Bezuidenhout, A Simionescu… - Biomaterials, 2014 - Elsevier
There is a significant need for small diameter vascular grafts to be used in peripheral
vascular surgery; however autologous grafts are not always available, synthetic grafts …

Transmural capillary ingrowth is essential for confluent vascular graft healing

T Pennel, D Bezuidenhout, J Koehne, NH Davies… - Acta biomaterialia, 2018 - Elsevier
Spontaneous endothelialization of synthetic vascular grafts may occur via three independent
or concurrent modalities: transanastomotic (TA) outgrowth, transmural (TM) ingrowth or …

Dual electrospinning with sacrificial fibers for engineered porosity and enhancement of tissue ingrowth

J Voorneveld, A Oosthuysen, T Franz… - … Research Part B …, 2017 - Wiley Online Library
Porosity, pore size and pore interconnectivity are critical factors for cellular infiltration into
electrospun scaffolds. This study utilized dual electrospinning with sacrificial fiber extraction …