[HTML][HTML] Biological functions of RBP4 and its relevance for human diseases

JS Steinhoff, A Lass, M Schupp - Frontiers in Physiology, 2021 - frontiersin.org
Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …

[HTML][HTML] Vitamin A metabolism: an update

DN D'Ambrosio, RD Clugston, WS Blaner - Nutrients, 2011 - mdpi.com
Retinoids are required for maintaining many essential physiological processes in the body,
including normal growth and development, normal vision, a healthy immune system, normal …

[HTML][HTML] Origin and function of activated fibroblast states during zebrafish heart regeneration

B Hu, S Lelek, B Spanjaard, H El-Sammak… - Nature …, 2022 - nature.com
The adult zebrafish heart has a high capacity for regeneration following injury. However, the
composition of the regenerative niche has remained largely elusive. Here, we dissected the …

Retinoids, retinoic acid receptors, and cancer

XH Tang, LJ Gudas - Annual Review of Pathology: Mechanisms …, 2011 - annualreviews.org
Retinoids (ie, vitamin A, all-trans retinoic acid, and related signaling molecules) induce the
differentiation of various types of stem cells. Nuclear retinoic acid receptors mediate most but …

[HTML][HTML] Chemistry of the retinoid (visual) cycle

PD Kiser, M Golczak, K Palczewski - Chemical reviews, 2014 - ACS Publications
As succinctly summarized by Wolf, 1 lack of vitamin A (all-trans-retinol) was recognized by
ancient Egyptians as causing a visual deficiency involving the retina and cornea that could …

[HTML][HTML] Retinol and retinyl esters: biochemistry and physiology: thematic review series: fat-soluble vitamins: vitamin A

SM O'Byrne, WS Blaner - Journal of lipid research, 2013 - ASBMB
By definition, a vitamin is a substance that must be obtained regularly from the diet. Vitamin
A must be acquired from the diet, but unlike most vitamins, it can also be stored within the …

[HTML][HTML] Absorption of vitamin A and carotenoids by the enterocyte: focus on transport proteins

E Reboul - Nutrients, 2013 - mdpi.com
Vitamin A deficiency is a public health problem in most developing countries, especially in
children and pregnant women. It is thus a priority in health policy to improve preformed …

Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage

WS Blaner, SM O'Byrne, N Wongsiriroj, J Kluwe… - … et Biophysica Acta (BBA …, 2009 - Elsevier
The majority of retinoid (vitamin A and its metabolites) present in the body of a healthy
vertebrate is contained within lipid droplets present in the cytoplasm of hepatic stellate cells …

[HTML][HTML] Retinitis pigmentosa: progress in molecular pathology and biotherapeutical strategies

W Liu, S Liu, P Li, K Yao - International Journal of Molecular Sciences, 2022 - mdpi.com
Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by
photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in …

Carotenoid metabolism at the intestinal barrier

J von Lintig, J Moon, J Lee, S Ramkumar - Biochimica et Biophysica Acta …, 2020 - Elsevier
Carotenoids exert a rich variety of physiological functions in mammals and are beneficial for
human health. These lipids are acquired from the diet and metabolized to apocarotenoids …