Biomarkers for diagnosis of neonatal sepsis: a literature review

D Sharma, N Farahbakhsh, S Shastri… - The Journal of Maternal …, 2018 - Taylor & Francis
Sepsis is an important cause of mortality and morbidity in neonatal populations. There has
been constant search of an ideal sepsis biomarker that have high sensitivity, specificity …

Effect of kidney function on drug kinetics and dosing in neonates, infants, and children

F Rodieux, M Wilbaux, JN van den Anker… - Clinical …, 2015 - Springer
Neonates, infants, and children differ from adults in many aspects, not just in age, weight,
and body composition. Growth, maturation and environmental factors affect drug kinetics …

Prenatal and postnatal management of congenital pulmonary airway malformation

M David, R Lamas-Pinheiro, T Henriques-Coelho - Neonatology, 2016 - karger.com
Congenital pulmonary airway malformation (CPAM) is one of the most common lung lesions
detected prenatally. Despite the research efforts made in the past few years, controversy and …

[HTML][HTML] Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery

DB Kell, R Goodacre - Drug Discovery Today, 2014 - Elsevier
Highlights•We now have metabolic network models; the metabolome is represented by their
nodes.•Metabolite levels are sensitive to changes in enzyme activities.•Drugs hitchhike on …

Metabolomics Application in Maternal‐Fetal Medicine

V Fanos, L Atzori, K Makarenko… - BioMed research …, 2013 - Wiley Online Library
Metabolomics in maternal‐fetal medicine is still an “embryonic” science. However, there is
already an increasing interest in metabolome of normal and complicated pregnancies, and …

Urinary 1H-NMR and GC-MS metabolomics predicts early and late onset neonatal sepsis

V Fanos, P Caboni, G Corsello, M Stronati… - Early human …, 2014 - Elsevier
The purpose of this article is to study one of the most significant causes of neonatal morbidity
and mortality: neonatal sepsis. This pathology is due to a bacterial or fungal infection …

Precision medicine for neonatal sepsis

S Ng, T Strunk, P Jiang, T Muk, PT Sangild… - Frontiers in molecular …, 2018 - frontiersin.org
Neonatal sepsis remains a significant cause of morbidity and mortality especially in the
preterm infant population. The ability to promptly and accurately diagnose neonatal sepsis …

Metabolomics reveals dynamic metabolic changes associated with age in early childhood

CY Chiu, KW Yeh, G Lin, MH Chiang, SC Yang… - PloS one, 2016 - journals.plos.org
Objectives A detailed understanding of the metabolic processes governing rapid growth in
early life is still lacking. The aim of this study was to investigate the age-related metabolic …

Metabolomics and the great obstetrical syndromes–GDM, PET, and IUGR

A Dessì, FC Marincola, V Fanos - … Practice & Research Clinical Obstetrics & …, 2015 - Elsevier
Gestational diabetes mellitus, intrauterine growth restriction, and preeclamptic toxemia are
common pregnancy complications that can have detrimental effects on morbidity and …

Neonatal sepsis biomarkers: where are we now?

M Gilfillan, V Bhandari - Research and Reports in Neonatology, 2019 - Taylor & Francis
Given that neonatal sepsis remains an important factor contributing to mortality and
morbidity in neonates, identification of accurate biomarkers to aid in its timely and accurate …