What's in a Gene? The Outstanding Diversity of MAPT
D Ruiz-Gabarre, A Carnero-Espejo, J Ávila… - Cells, 2022 - mdpi.com
Tau protein is a microtubule-associated protein encoded by the MAPT gene that carries out
a myriad of physiological functions and has been linked to certain pathologies collectively …
a myriad of physiological functions and has been linked to certain pathologies collectively …
Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density
Alzheimer's disease begins with mild memory loss and slowly destroys memory and
thinking. Cognitive impairment in Alzheimer's disease has been associated with the …
thinking. Cognitive impairment in Alzheimer's disease has been associated with the …
Tau target identification reveals NSF‐dependent effects on AMPA receptor trafficking and memory formation
E Prikas, E Paric, PR Asih, K Stefanoska… - The EMBO …, 2022 - embopress.org
Microtubule‐associated protein tau is a central factor in Alzheimer's disease and other
tauopathies. However, the physiological functions of tau are unclear. Here, we used …
tauopathies. However, the physiological functions of tau are unclear. Here, we used …
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3
C Tapia-Monsalves, MA Olesen… - Molecular and Cellular …, 2023 - Elsevier
Abstract During Alzheimer's (AD), tau protein suffers from abnormal post-translational
modifications, including cleaving by caspase-3. These tau forms affect synaptic plasticity …
modifications, including cleaving by caspase-3. These tau forms affect synaptic plasticity …
Lipid peroxidation induced ApoE receptor-ligand disruption as a unifying hypothesis underlying sporadic Alzheimer's disease in humans
CE Ramsden, GS Keyes, E Calzada… - Journal of …, 2022 - content.iospress.com
Background: Sporadic Alzheimer's disease (sAD) lacks a unifying hypothesis that can
account for the lipid peroxidation observed early in the disease, enrichment of ApoE in the …
account for the lipid peroxidation observed early in the disease, enrichment of ApoE in the …
Disease progression and genetic risk factors in the primary tauopathies
WJ Scotton - 2023 - search.proquest.com
The primary tauopathies are a group of progressive neurodegenerative diseases within the
frontotemporal lobar degeneration spectrum (FTLD) characterised by the accumulation of …
frontotemporal lobar degeneration spectrum (FTLD) characterised by the accumulation of …
Formation, regulation and dynamics of phase separated postsynaptic density condensates with Tau and Fyn
Z Shen - 2024 - ediss.uni-goettingen.de
Formation, regulation and dynamics of phase- separated postsynaptic density condensates
with Tau and Fyn Zheng Shen Page 1 i Formation, regulation and dynamics of phaseseparated …
with Tau and Fyn Zheng Shen Page 1 i Formation, regulation and dynamics of phaseseparated …
[HTML][HTML] The Role of TRKB Receptor Complex Proteins and the Lipid Environment In the Mechanism of Antidepressant Drug Action
SM Fred - 2022 - helda.helsinki.fi
Brain plasticity, in its simplest definition, is the ability of brain to change itself. This
phenomenon, which is important for the development and wiring of neuronal networks, is …
phenomenon, which is important for the development and wiring of neuronal networks, is …
The Role of Tau in Depression Via the Microtubule Dynamic by Several Regulators: A Review
H Wang, C Yang, Z Zhu - Available at SSRN 4129732 - papers.ssrn.com
Objectives: There is growing evidence that the tau protein plays an essential role in
Alzheimer's disease. However, an increasing number of researchers have recently focus on …
Alzheimer's disease. However, an increasing number of researchers have recently focus on …