Nanophytomedicines for the prevention of metabolic syndrome: a pharmacological and biopharmaceutical review

Z Nouri, M Hajialyani, Z Izadi… - … in Bioengineering and …, 2020 - frontiersin.org
Metabolic syndrome includes a series of metabolic abnormalities that leads to diabetes
mellitus and cardiovascular diseases. Plant extracts, due to their unique advantages like anti …

Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice

H Yang, T Yang, C Heng, Y Zhou, Z Jiang… - Phytotherapy …, 2019 - Wiley Online Library
Multiphase pathological processes involve in Type 2 diabetes (T2DM)‐induced
nonalcoholic fatty liver disease (NAFLD). However, the therapies are quite limited. In the …

Stem Cell therapy in combination with naturopathy: Current progressive management of diabetes and associated complications

A Saha, A Samadder, S Nandi - Current Topics in Medicinal …, 2023 - ingentaconnect.com
Background: Diabetes is a chronic metabolic disorder having a global prevalence of nearly
doubled over the last 30 years and has become one of the major health concerns …

Protective role of morin, a flavonoid, against high glucose induced oxidative stress mediated apoptosis in primary rat hepatocytes

R Kapoor, P Kakkar - 2012 - journals.plos.org
Apoptosis is an early event of liver damage in diabetes and oxidative stress has been linked
to accelerate the apoptosis in hepatocytes. Therefore, the compounds that can scavenge …

Morroniside interaction with poly (ADP-ribose) polymerase accentuates metabolic mitigation of alloxan-induced genotoxicity and hyperglycaemia: a molecular docking …

S Dey, I Nagpal, P Sow, R Dey… - Journal of …, 2023 - Taylor & Francis
The present study tends to evaluate the possible potential of bio-active Morroniside (MOR),
against alloxan (ALX)-induced genotoxicity and hyperglycaemia. In silico prediction …

Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria

S Das, J Das, A Samadder… - Experimental …, 2012 - journals.sagepub.com
We isolated apigenin (5, 7, 4'-trihydroxy flavone) from ethanolic extract of Lycopodium
clavatum (LC) used as a homeopathic mother tincture for treatment of various diseases. We …

Strategic formulation of apigenin-loaded PLGA nanoparticles for intracellular trafficking, DNA targeting and improved therapeutic effects in skin melanoma in vitro

S Das, J Das, A Samadder, A Paul, AR Khuda-Bukhsh - Toxicology letters, 2013 - Elsevier
The aim of the present study was the evaluation of anti-proliferative potentials of apigenin
(Ap),(a dietary flavonoid) loaded in poly (lactic-co-glycolide) nanoparticles (NAp) in A375 …

[HTML][HTML] The potentized homeopathic drug, Lycopodium clavatum (5C and 15C) has anti-cancer effect on hela cells in vitro.

A Samadder, S Das, J Das, A Paul, N Boujedaini… - Journal of acupuncture …, 2013 - Elsevier
Cancer is a disease that needs a multi-faceted approach from different systems of medicine.
The purpose of this study was to evaluate whether homeopathically-potentized ultra-high …

[HTML][HTML] Apigenin, a bioactive flavonoid from Lycopodium clavatum, stimulates nucleotide excision repair genes to protect skin keratinocytes from ultraviolet B-induced …

S Das, J Das, A Paul, A Samadder… - Journal of acupuncture …, 2013 - Elsevier
In this study, we examined the antioxidative and the DNA protective potentials of apigenin, a
flavonoid polyphenol isolated from Lycopodium clavatum, in both in-vitro (HaCaT skin …

Lipotoxic impairment of mitochondrial function in β-cells: A review

A Römer, T Linn, SF Petry - Antioxidants, 2021 - mdpi.com
Lipotoxicity is a major contributor to type 2 diabetes mainly promoting mitochondrial
dysfunction. Lipotoxic stress is mediated by elevated levels of free fatty acids through …