ABSTRACT SQSTM1 (also known as p62) is a multifunctional stress-inducible scaffold
protein involved in diverse cellular processes. Its functions are tightly regulated through an …

p62/SQSTM 1 is a multifunctional signaling hub and autophagy adaptor with many binding
partners, which allow it to activate mTORC 1‐dependent nutrient sensing, NF‐κB‐mediated …

Alzheimer's disease (AD) is a progressive neurodegeneration characterized by neuron
death ending in memory and cognitive decline. A major concern in AD research is the …

The literature has supported the concept of mesenchymal stromal cells (MSCs) in bone
regeneration as one of the most important applications in oro-maxillofacial reconstructions …

Abstract p62 (also known as SQSTM1) is widely used as a predictor of autophagic flux, a
process that allows the degradation of harmful and unnecessary components through …

p62, a protein capable of binding both ubiquitin and autophagy substrates, is well
established as a key regulator in cancer and neurodegenerative diseases. Recently, there …

Abstract P62/SQSTM1, a multi-domain protein that regulates inflammation, apoptosis, and
autophagy, has been linked to age-related pathologies. For example, previously we …

Inflammation is the preceding condition for the development of mild and severe pathological
conditions, including various forms of osteopenia, cancer, metabolic syndromes …

Elenagen is a plasmid encoding p62/SQSTM1, the first DNA vaccine possessing two
mutually complementing mechanisms of action: it elicits immune response against p62 and …

The p62 (also named sequestosome1/SQSTM1) is multidomain and multifunctional protein
associated with several physiological and pathological conditions. A number of studies …