[HTML][HTML] The not-so-good, the bad and the ugly: HPV E5, E6 and E7 oncoproteins in the orchestration of carcinogenesis

O Basukala, L Banks - Viruses, 2021 - mdpi.com
Infection with HPV starts with the access of the viral particles to basal cells in the epidermis,
potentially via microtraumas to the skin. The basal cells are able to keep away these …

[HTML][HTML] Link between chronic inflammation and human papillomavirus-induced carcinogenesis

JV Fernandes… - Oncology …, 2015 - spandidos-publications.com
Inflammation is a defense strategy against invading agents and harmful molecules that is
activated immediately following a stimulus, and involves the release of cytokines and …

CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing …

DC Strachan, B Ruffell, Y Oei, MJ Bissell… - …, 2013 - Taylor & Francis
Increased numbers of tumor-infiltrating macrophages correlate with poor disease outcome in
patients affected by several types of cancer, including breast and prostate carcinomas. The …

[HTML][HTML] Immunopathogenesis of HPV-associated cancers and prospects for immunotherapy

S Smola - Viruses, 2017 - mdpi.com
Human papillomavirus (HPV) infection is a causative factor for various cancers of the
anogenital region and oropharynx, and is supposed to play an important cofactor role for …

The role of inflammation in HPV carcinogenesis

E Boccardo, AP Lepique, LL Villa - Carcinogenesis, 2010 - academic.oup.com
The role of inflammation in human papillomavirus (HPV) infection and disease is complex
since it involves responses capable of preventing initial infections, clearing those ongoing …

Multiple roles for CCR2 during fracture healing

Z Xing, C Lu, D Hu, Y Yu, X Wang… - Disease models & …, 2010 - journals.biologists.com
Bone injury induces an inflammatory response that involves neutrophils, macrophages and
other inflammatory cells. The recruitment of inflammatory cells to sites of injury occurs in …

[HTML][HTML] Oxidative stress and HPV carcinogenesis

F De Marco - Viruses, 2013 - mdpi.com
Extensive experimental work has conclusively demonstrated that infection with certain types
of human papillomaviruses, the so-called high-risk human papillomavirus (HR-HPV) …

Stromal fibroblasts induce CCL20 through IL6/C/EBPβ to support the recruitment of Th17 cells during cervical cancer progression

B Walch-Rückheim, R Mavrova, M Henning, B Vicinus… - Cancer research, 2015 - AACR
Cervical cancer is a consequence of persistent infection with human papillomaviruses
(HPV). Progression to malignancy is linked to an inflammatory microenvironment comprising …

HPV infection: immunological aspects and their utility in future therapy

E Deligeoroglou, A Giannouli… - … in obstetrics and …, 2013 - Wiley Online Library
High prevalence and mortality rates of cervical cancer create an imperative need to clarify
the uniqueness of HPV (Human Papillomavirus) infection, which serves as the key causative …

HPV16 tumor associated macrophages suppress antitumor T cell responses

AP Lepique, KRP Daghastanli, IM Cuccovia… - Clinical Cancer …, 2009 - AACR
Purpose: High-risk human papillomavirus (HPV) is the main etiologic factor for cervical
cancer. The severity of HPV-associated cervical lesions has been correlated to the number …