Background: Radiation dose escalation is limited by the high incidence of pulmonary and
esophageal toxicity, leading to calls for the omission of elective nodal irradiation (ENI) and …

Purpose Dose escalation has been shown to improve local control in non–small-cell lung
cancer (NSCLC) treated with definitive radiation therapy, but with increased complications …

Purpose: Dose escalation using three-dimensional conformal radiation therapy (3D-CRT)
has been investigated as a means to improve local control. However, with higher doses, the …

Locally advanced non-small cell lung cancer (LA-NSCLC) is a heterogeneous disease,
encompassing stage IIIA, for which surgery in combination with chemotherapy and/or …

Purpose: To establish the recurrence patterns when elective mediastinal irradiation was
omitted, patients with Stage III non-small-cell lung cancer were treated with sequential …

The treatment of non-small cell lung cancer has continued to evolve with the advent of
improved staging technologies, chemotherapeutic agents, and methods of radiation …

Purpose: To evaluate in-field progression and survival of patients with unresectable non-
small cell lung cancer (NSCLC) in relation to adequacy of coverage of thoracic regional …

With 40,000 to 50,000 patients diagnosed annually, stage III lung cancer represents
approximately one third of all non–small-cell lung cancer cases. It is a heterogeneous …

Purpose: When mediastinal lymph nodes are clinically uninvolved in the setting of
inoperable non-small cell lung cancer, whether conventional radiation techniques or three …

Background Radiotherapy (RT) is a key treatment modality in the curative treatment of
patients with non-small cell lung cancer (NSCLC). Incorrect definition of the gross, or clinical …