Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system

DL Feinstein, S Kalinin, D Braun - Journal of neurochemistry, 2016 - Wiley Online Library
Aside from its roles in as a classical neurotransmitter involved in regulation of behavior,
noradrenaline (NA) has other functions in the CNS. This includes restricting the …

Systematic review and meta-analysis of genetic risk factors for neuropathic pain

A Veluchamy, HL Hebert, W Meng, CNA Palmer… - Pain, 2018 - journals.lww.com
Neuropathic pain (NP) is an increasingly common chronic pain state and a major health
burden, affecting approximately 7% to 10% of the general population. Emerging evidence …

Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel …

O Van Hecke, PR Kamerman, N Attal, R Baron… - Pain, 2015 - journals.lww.com
For genetic research to contribute more fully to furthering our knowledge of neuropathic
pain, we require an agreed, valid, and feasible approach to phenotyping, to allow …

The potential roles of amino acids and their major derivatives in the management of multiple sclerosis

S Pashaei, R Yarani, P Mohammadi… - Amino acids, 2022 - Springer
Recently, we reviewed the important role of carbohydrates and lipids metabolism in different
clinical aspects of multiple sclerosis (MS) disease. In the current paper, we aimed to review …

The blood–brain barrier-permeable catechol-O-methyltransferase inhibitor dinitrocatechol suppresses experimental autoimmune encephalomyelitis

PE Polak, SX Lin, D Pelligrino, DL Feinstein - Journal of neuroimmunology, 2014 - Elsevier
Reduced levels of noradrenaline (NA) in CNS of multiple sclerosis patients could be due to
metabolism by catechol-O-methyltransferase (COMT). In mice immunized with myelin …

An observational study of the impact of genetic testing for pain perception in the clinical management of chronic non-cancer pain

M Sharma, S Kantorovich, C Lee, N Anand… - Journal of psychiatric …, 2017 - Elsevier
Objective Pain levels are a key metric in clinical care. However, the assessment of pain is
limited to basic questionnaires and physician interpretation, which yield subjective data …

Identification of key genes and signaling pathway in the pathogenesis of Huntington's disease via bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Huntington's disease (HD) is the primary cause of progressive motor deficits, psychiatric
symptoms, and cognitive impairment. The exact molecular mechanisms of HD pathogenesis …

[HTML][HTML] Genetics of CPSP

S Sciberras - Pain Management-From Acute to Chronic and …, 2024 - intechopen.com
Various polymorphisms in several genes appear to be involved in the development of
chronic post-surgical pain (CPSP). These genes are involved in the transduction …

[PDF][PDF] Multipl Skleroz'lu Bireylerde Kanada Aktivite Performans Ölçümü'nün Türkçe Kültürel Adaptasyonu

B Torpil - Geçerlilik ve Güvenilirliği, 2017 - researchgate.net
Lisans Tezi, Ankara, 2017. Bu araştırma, Multipl Skleroz'lu (MS) bireylerde kişi merkezli bir
sonuç ölçümü olan Kanada Aktivite Performans Ölçümü'nün (KAPÖ) Türkçe'ye uyarlanması …

[PDF][PDF] Prise en charge du douloureux chronique en périopératoire

A Belbachir, M Olivier, JP Estebe - Thorax, 2018 - researchgate.net
Les douleurs chroniques postchirurgicales (DCPC) sont des douleurs qui persistent plus de
trois à six mois. Leur incidence est évaluée à environ 30%. Elles se répartissent en trois …