Quorum sensing (QS), a density-dependent signaling mechanism of microbial cells, involves
an exchange and sense of low molecular weight signaling compounds called autoinducers …

Melioidosis, infection with Burkholderia pseudomallei, is being recognised with increasing
frequency and is probably more common than currently appreciated. Treatment …

The number of effective therapeutic strategies against biofilms is limited; development of
novel therapies is urgently needed to treat a variety of biofilm-associated infections. Quorum …

Indiscriminate use of antibiotics to treat microbial pathogens has caused emergence of
multiple drug resistant strains. Most infectious diseases are caused by microbes that are …

The discovery of antibiotics has revolutionized the medicine and treatment of microbial
infections. However, the current scenario has highlighted the difficulties in marketing new …

Quorum sensing was once considered a way in which a species was able to sense its cell
density and regulate gene expression accordingly. However, it is now becoming apparent …

Tyrosol is a quorum-sensing molecule of Candida albicans able to induce hyphal
development in the early and intermediate stages of biofilm growth. In the present study, we …

Aims The aim of this study was to analyse the in vitro activity of farnesol alone and combined
with the antibacterial drugs amoxicillin, doxycycline, ceftazidime and sulfamethoxazole …

Background: Farnesol is an acyclic sesquiterpene alcohol, endogenously synthesized via
the ergosterol pathway. It is a quorum sensing molecule (QSM) that was first discovered in …

It is believed that most microbial infections are caused by pathogens organized in biofilms.
Recently, it was shown that the dimorphic fungus Histoplasma capsulatum, estimated to be …