Applications of phyto-nanotechnology for the treatment of neurodegenerative disorders

T Bhattacharya, GAB Soares, H Chopra, MM Rahman… - Materials, 2022 - mdpi.com
The strategies involved in the development of therapeutics for neurodegenerative disorders
are very complex and challenging due to the existence of the blood-brain barrier (BBB), a …

Towards improvements for penetrating the blood–brain barrier—recent progress from a material and pharmaceutical perspective

Q He, J Liu, J Liang, X Liu, W Li, Z Liu, Z Ding, D Tuo - Cells, 2018 - mdpi.com
The blood–brain barrier (BBB) is a critical biological structure that prevents damage to the
brain and maintains its bathing microenvironment. However, this barrier is also the obstacle …

Curcumin's nanomedicine formulations for therapeutic application in neurological diseases

B Salehi, D Calina, AO Docea, N Koirala… - Journal of Clinical …, 2020 - mdpi.com
The brain is the body's control center, so when a disease affects it, the outcomes are
devastating. Alzheimer's and Parkinson's disease, and multiple sclerosis are brain diseases …

Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease

B Fonseca-Santos, MPD Gremião… - International Journal of …, 2015 - Taylor & Francis
Alzheimer's disease is a neurological disorder that results in cognitive and behavioral
impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs …

Considerations around the SARS-CoV-2 spike protein with particular attention to COVID-19 brain infection and neurological symptoms

K Hassanzadeh, H Perez Pena, J Dragotto… - ACS chemical …, 2020 - ACS Publications
Spike protein (S protein) is the virus “key” to infect cells and is able to strongly bind to the
human angiotensin-converting enzyme2 (ACE2), as has been reported. In fact, Spike …

Nanoformulations of herbal extracts in treatment of neurodegenerative disorders

SZ Moradi, S Momtaz, Z Bayrami… - … in bioengineering and …, 2020 - frontiersin.org
Nanotechnology is one of the methods that influenced human life in different ways and is a
substantial approach that assists to overcome the multiple limitations of various diseases …

Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges

MM Wen, NS El-Salamouni, WM El-Refaie… - Journal of controlled …, 2017 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the
rapidly growing elderly population in the developing world. The currently FDA approved …

Recent advances in the nanoparticles synthesis using plant extract: Applications and future recommendations

FE Ettadili, S Aghris, F Laghrib, A Farahi… - Journal of Molecular …, 2022 - Elsevier
The Nano-biotechnology represents the intersection of nanotechnology and biotechnology
and is a promising field of nanotechnology. Recently, the need of making biocompatible …

Neurotropism of SARS-CoV-2 and neurological diseases of the central nervous system in COVID-19 patients

S Veleri - Experimental brain research, 2022 - Springer
The devastating COVID-19 pandemic is caused by the SARS-CoV-2 virus. It primarily affects
the lung and induces acute respiratory distress leading to a decrease in oxygen supply to …

Neuroprotection by curcumin: A review on brain delivery strategies

A Askarizadeh, GE Barreto, NC Henney… - International journal of …, 2020 - Elsevier
Neurodegenerative diseases are a major global public health concern in the elderly
population but therapeutic options are limited. Curcumin is a hydrophobic polyphenol …