Progress and prospects on vaccine development against monkeypox infection

MJ Saadh, T Ghadimkhani, N Soltani… - Microbial …, 2023 - Elsevier
The monkeypox virus (MPOX) is an uncommon zoonotic illness brought on by an
orthopoxvirus (OPXV). MPOX can occur with symptoms similar to smallpox. Since April 25 …

Knowledge and attitudes of health care workers about monkeypox virus infection in Southern Italy

G Miraglia del Giudice, G Della Polla… - Frontiers in Public …, 2023 - frontiersin.org
Background This present survey sought to investigate the level of knowledge and the
attitudes pertaining the monkeypox (mpox) virus infection among a sample of health care …

[HTML][HTML] Mechanisms of immune evasion of monkeypox virus

M Zandi, M Shafaati, F Hosseini - Frontiers in microbiology, 2023 - frontiersin.org
The mpox (disease caused by the monkeypox virus) epidemic in 2022 provides a good
opportunity to study the immune response to mpox. Vaccinia virus-infected monocytes could …

Pathogenicity and virulence of monkeypox at the human-animal-ecology interface

MM Islam, P Dutta, R Rashid, SS Jaffery, A Islam… - Virulence, 2023 - Taylor & Francis
Monkeypox (Mpox) was mostly limited to Central and Western Africa, but recently it has been
reported globally. The current review presents an update on the virus, including ecology and …

Proteomics-based vaccine targets annotation and design of subunit and mRNA-based vaccines for Monkeypox virus (MPXV) against the recent outbreak

Y Jin, A Fayyaz, A Liaqat, A Khan, A Alshammari… - Computers in Biology …, 2023 - Elsevier
Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and
fatalities globally. To date, no specific vaccine or small molecule therapeutic choices are …

Design, evaluation, and immune simulation of potentially universal multi-epitope mpox vaccine candidate: focus on DNA vaccine

N Rcheulishvili, J Mao, D Papukashvili… - Frontiers in …, 2023 - frontiersin.org
Monkeypox (mpox) is a zoonotic infectious disease caused by the mpox virus. Mpox
symptoms are similar to smallpox with less severity and lower mortality. As yet mpox virus is …

Characterizing the acute antibody response of monkeypox and MVA‐BN vaccine following an Australian outbreak

W Asquith, L Hueston, D Dwyer, J Kok… - Journal of Medical …, 2024 - Wiley Online Library
In response to the emergence of the monkeypox virus (MPXV) in Australia in May 2022, we
developed and evaluated indirect immunofluorescence assays (IFA) for MPXV and Vaccinia …

Monkeypox virus replication underlying circadian rhythm networks

M Zandi, M Shafaati, P Shapshak… - Journal of …, 2023 - Springer
The mammalian brain has an endogenous central circadian clock that regulates central and
peripheral cellular activities. At the molecular level, this day-night cycle induces the …

The prospective outcome of the monkeypox outbreak in 2022 and characterization of monkeypox disease immunobiology

MS Qudus, X Cui, M Tian, U Afaq, M Sajid… - Frontiers in Cellular …, 2023 - frontiersin.org
A new threat to global health re-emerged with monkeypox's advent in early 2022. As of
November 10, 2022, nearly 80,000 confirmed cases had been reported worldwide, with …

The Global Health Threat of Monkeypox Virus: Understanding Its Biology, Transmission, and Potential Therapeutic Interventions

Y He, Y Tang, C Wang, Z Zhou, W Li… - Infection and Drug …, 2023 - Taylor & Francis
Monkeypox virus (MPXV), a member of the Orthopoxvirus genus, shares its genus with
Variola virus (VARV), the causative agent of smallpox, and Vaccinia virus (VACV), used for …