Molecular pathways in protecting the liver from ischaemia/reperfusion injury: a 2015 update

J Gracia-Sancho, A Casillas-Ramirez… - Clinical Science, 2015 - portlandpress.com
Ischaemia/reperfusion injury is an important cause of liver damage during surgical
procedures such as hepatic resection and liver transplantation, and represents the main …

[PDF][PDF] Use of steatotic grafts in liver transplantation: current status

AI Álvarez‐Mercado, J Gulfo… - Liver …, 2019 - Wiley Online Library
In the field of liver transplantation, the demand for adequate allografts greatly exceeds the
supply. Therefore, expanding the donor pool to match the growing demand is mandatory …

Reduced delivery of epididymal adipocyte‐derived exosomal resistin is essential for melatonin ameliorating hepatic steatosis in mice

B Rong, R Feng, C Liu, Q Wu… - Journal of Pineal …, 2019 - Wiley Online Library
Adipocyte‐derived exosomes (Exos) serve as bioinformation‐containing messengers in cell‐
to‐cell communications, and numerous reports demonstrate that resistin, an adipokine, is …

IRE1α aggravates ischemia reperfusion injury of fatty liver by regulating phenotypic transformation of kupffer cells

F Yang, S Wang, Y Liu, Y Zhou, L Shang… - Free Radical Biology …, 2018 - Elsevier
Fatty liver is one of the widely accepted marginal donor for liver transplantation, but is also
more sensitive to ischemia and reperfusion injury (IRI) and produces more reactive oxygen …

TNFα‐Mediated Necroptosis Aggravates Ischemia‐Reperfusion Injury in the Fatty Liver by Regulating the Inflammatory Response

F Yang, L Shang, S Wang, Y Liu, H Ren… - Oxidative Medicine …, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is more sensitive to ischemia and reperfusion
injury (IRI), while there are no effective methods to alleviate IRI. Necroptosis, also known as …

Increased serum resistin levels correlate with psoriasis: a meta-analysis

H Huang, E Shen, S Tang, X Tan, X Guo… - Lipids in Health and …, 2015 - Springer
Background Recent studies implicate adipokines in the pathogenesis of inflammatory
diseases, including psoriasis. In this study we evaluated the significance of serum resistin …

SOD2 overexpression in bone marrow‑derived mesenchymal stem cells ameliorates hepatic ischemia/reperfusion injury

Q Li, W Zhang, E Xiao - Molecular Medicine Reports, 2021 - spandidos-publications.com
Hepatic ischemia/reperfusion injury (HIRI) is a complex pathophysiological process that may
develop after liver transplantation and resection surgery, as well as in uncontrolled clinical …

[HTML][HTML] Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis

L Zhang, M Wang, R An, J Dai, S Liu… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
Methods A mouse model of hepatic steatosis was established by feeding the mice with a
high-fat diet. In vitro experiments were performed using AML12 normal mouse liver cells and …

Association between adipokines and critical illness outcomes

T Hajri, M Gharib, S Kaul… - Journal of Trauma and …, 2017 - journals.lww.com
BACKGROUND Adipose tissue is an endocrine organ that plays a critical role in immunity
and metabolism by virtue of a large number of hormones and cytokines, collectively termed …

NAMPT inhibition reduces macrophage inflammation through the NAD+/PARP1 pathway to attenuate liver ischemia–reperfusion injury

J Lu, M Wang, Y Chen, H Song, D Wen, J Tu… - Chemico-Biological …, 2023 - Elsevier
Background Liver ischemia–reperfusion injury (IRI) is a major complication in the
perioperative period and often leads to liver failure and even systemic inflammation …