Chemokines in colon cancer progression

SN Jia, YB Han, R Yang, ZC Yang - Seminars in cancer biology, 2022 - Elsevier
Colon cancer is a major human cancer accounting for about a tenth of all cancer cases thus
making it among the top three cancers in terms of incidence as well as mortality. Metastasis …

[HTML][HTML] Immunomodulation by gut microbiome on gastrointestinal cancers: focusing on colorectal cancer

RK Al-Ishaq, L Koklesova, P Kubatka, D Büsselberg - Cancers, 2022 - mdpi.com
Simple Summary A symbiotic relationship with the host gut microbiome influences the
immune system's development, functions, and activities. In the mucosa, the gut microbiome …

[HTML][HTML] TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells

JA Woznicki, N Saini, P Flood, S Rajaram, CM Lee… - Cell death & …, 2021 - nature.com
Rewiring of host cytokine networks is a key feature of inflammatory bowel diseases (IBD)
such as Crohn's disease (CD). Th1-type cytokines—IFN-γ and TNF-α—occupy critical nodes …

[HTML][HTML] Regulation of CEACAM family members by IBD-associated triggers in intestinal epithelial cells, their correlation to inflammation and relevance to IBD …

G Saiz-Gonzalo, N Hanrahan, V Rossini… - Frontiers in …, 2021 - frontiersin.org
Carcinoembryogenic antigen cellular adhesion molecules (CEACAMs) are intercellular
adhesion molecules highly expressed in intestinal epithelial cells. CEACAM1,-3,-5,-6,-7 are …

[HTML][HTML] Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis

M Shao, Y Yan, F Zhu, X Yang, Q Qi, F Yang… - Frontiers in …, 2022 - frontiersin.org
Intestinal barrier disruption due to the intestinal epithelial cells'(IECs) death is one of the
critical pathological features of inflammatory bowel diseases (IBDs). SM934, an artemisinin …

[HTML][HTML] Ginseng stem-and-leaf saponins mitigate chlorpyrifos-evoked intestinal toxicity in vivo and in vitro: oxidative stress, inflammatory response and apoptosis

S Liu, X Zhu, H Pei, Y Zhao, Y Zong, W Chen… - International Journal of …, 2023 - mdpi.com
In recent years, the phenomenon of acute poisoning and organ damage caused by
organophosphorus pesticides (OPs) has been a frequent occurrence. Chlorpyrifos (CPF) is …

[HTML][HTML] A new strategy for treating colorectal cancer: Regulating the influence of intestinal flora and oncolytic virus on interferon

J Yi, P Lin, Q Li, A Zhang, X Kong - Molecular Therapy-Oncolytics, 2023 - cell.com
Colorectal cancer (CRC) has the third highest incidence and the second highest mortality in
the world, which seriously affects human health, while current treatments methods for CRC …

Crosstalk between alternative splicing and inflammatory bowel disease: Basic mechanisms, biotechnological progresses and future perspectives

C Zou, X Zan, Z Jia, L Zheng, Y Gu, F Liu… - Clinical and …, 2023 - Wiley Online Library
Background Alternative splicing (AS) is an omnipresent regulatory mechanism of gene
expression that enables the generation of diverse splice isoforms from a single gene …

[HTML][HTML] BCL-G: 20 years of research on a non-typical protein from the BCL-2 family

ML Hartman, M Czyz - Cell Death & Differentiation, 2023 - nature.com
Proteins from the BCL-2 family control cell survival and apoptosis in health and disease, and
regulate apoptosis-unrelated cellular processes. BCL-Gonad (BCL-G, also known as BCL2 …

[HTML][HTML] Bioinformatics analysis of differentially expressed genes and protein–protein interaction networks associated with functional pathways in ulcerative colitis

F Cao, YS Cheng, L Yu, YY Xu… - Medical Science Monitor …, 2021 - ncbi.nlm.nih.gov
Bioinformatics Analysis of Differentially Expressed Genes and Protein–Protein Interaction
Networks Associated with Functional Pathways in Ulcerative Colitis - PMC Back to Top Skip to …