[HTML][HTML] Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases

G Cavalli, S Colafrancesco, G Emmi, M Imazio… - Autoimmunity …, 2021 - Elsevier
Abstract The interleukin (IL)-1 family member IL-1α is a ubiquitous and pivotal pro-
inflammatory cytokine. The IL-1α precursor is constitutively present in nearly all cell types in …

[HTML][HTML] The impact of oxidative stress in male infertility

A Mannucci, FR Argento, E Fini, ME Coccia… - Frontiers in Molecular …, 2022 - frontiersin.org
At present infertility is affecting about 15% of couples and male factor is responsible for
almost 50% of infertility cases. Oxidative stress, due to enhanced Reactive Oxygen Species …

Behçet syndrome: a contemporary view

H Yazici, E Seyahi, G Hatemi, Y Yazici - Nature Reviews Rheumatology, 2018 - nature.com
The presence of symptom clusters, regional differences in disease expression and
similarities with, for example, Crohn's disease suggest multiple pathological pathways are …

Single-cell analyses highlight the proinflammatory contribution of C1q-high monocytes to Behçet's disease

W Zheng, X Wang, J Liu, X Yu, L Li… - Proceedings of the …, 2022 - National Acad Sciences
Behçet's disease (BD) is a chronic vasculitis characterized by systemic immune aberrations.
However, a comprehensive understanding of immune disturbances in BD and how they …

Vascular Behçet syndrome: from pathogenesis to treatment

A Bettiol, F Alibaz-Oner, H Direskeneli… - Nature Reviews …, 2023 - nature.com
Behçet syndrome is a rare, chronic inflammatory disease of unknown aetiopathogenesis,
most commonly presenting with mucocutaneous and ocular manifestations. Vascular …

Immunopathogenesis of Behcet's disease

B Tong, X Liu, J Xiao, G Su - Frontiers in immunology, 2019 - frontiersin.org
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice

M Ząbczyk, RAS Ariëns, A Undas - Cardiovascular research, 2023 - academic.oup.com
Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

[HTML][HTML] Behçet's disease: an overview of etiopathogenesis

P Leccese, E Alpsoy - Frontiers in immunology, 2019 - frontiersin.org
Behçet's disease (BD) is a systemic inflammatory disease with a chronic, relapsing-remitting
course of unknown etiology hallmarked predominantly by mucocutaneous lesions and …

Vascular Behçet's syndrome: an update

G Emmi, A Bettiol, E Silvestri, G Di Scala… - Internal and emergency …, 2019 - Springer
Behçet's syndrome (BS) is a complex vasculitis, characterised by peculiar histological,
pathogenetic and clinical features. Superficial venous thrombosis (SVT) and deep vein …

Critical role of neutrophil extracellular traps (NETs) in patients with Behcet's disease

A Le Joncour, R Martos, S Loyau, N Lelay… - Annals of the …, 2019 - ard.bmj.com
Objectives Behçet's disease (BD) is a chronic systemic vasculitis. Thrombosis is a frequent
and life-threatening complication. The pathogenesis of BD is poorly understood and …