Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause
severe invasive infections upon ingestion with contaminated food. Clinically, listerial …

Listeria monocytogenes is a saprophytic gram-positive bacterium, and an opportunistic
foodborne pathogen that can produce listeriosis in humans and animals. It has evolved an …

Listeria monocytogenes is a foodborne intracellular bacterial pathogen leading to human
listeriosis. Despite a high mortality rate and increasing antibiotic resistance no clinically …

Pore-forming toxins (PFTs) are key virulence determinants produced and secreted by a
variety of human bacterial pathogens. They disrupt the plasma membrane (PM) by …

The year 2020 was shaped by the COVID-19 pandemic which killed more people than any
other infectious disease in this particular year. At the same time, the development of highly …

Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for
almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines …

To understand the contribution of mononuclear phagocytes (MNP), which include monocyte-
derived intestinal macrophages, to the pathogenesis of inflammatory bowel disease (IBD), it …

ABSTRACT The Gram-positive pathogen Listeria monocytogenes is able to promote its entry
into a diverse range of mammalian host cells by triggering plasma membrane remodeling …

Listeriolysin O (LLO) is an essential determinant of Listeria monocytogenes pathogenesis
that mediates the escape of L. monocytogenes from host cell vacuoles, thereby allowing …

Listeria monocytogenes causes listeriosis, a disease characterized by a high mortality rate
(up to 30%). Since the pathogen is highly tolerant to changing conditions (high and low …