Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases

M Sadeghi, S Dehnavi, A Asadirad, S Xu… - …, 2023 - Springer
Chemokines belong to the family of cytokines with chemoattractant properties that regulate
chemotaxis and leukocyte migration, as well as the induction of angiogenesis and …

Macrophage plasticity, polarization and function in response to curcumin, a diet-derived polyphenol, as an immunomodulatory agent

A Mohammadi, CN Blesso, GE Barreto… - The Journal of nutritional …, 2019 - Elsevier
Monocytes and macrophages are important cells of the innate immune system that have
diverse functions, including defense against invading pathogens, removal of dead cells by …

Curcumin: An effective inhibitor of interleukin-6

M Ghandadi, A Sahebkar - Current pharmaceutical design, 2017 - ingentaconnect.com
Curcumin is apolyphenolic cominflammatory effects of curcumin. Moreover, curcumin can be
considered as potential therapy against IL-6 involvepound found in the dietary spice …

Reductive metabolites of curcumin and their therapeutic effects

A Pandey, M Chaturvedi, S Mishra, P Kumar… - Heliyon, 2020 - cell.com
Curcumin, a secondary metabolite from the turmeric plant is one of the most promising
natural products, which has been studied extensively for decades. It has demonstrated …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

Gut microbiota as a prospective therapeutic target for curcumin: A review of mutual influence

W Zam - Journal of nutrition and metabolism, 2018 - Wiley Online Library
Background. Turmeric is a spice that has recently received much interest and has been
widely used in Ayurvedic medicine. Turmeric products are diarylheptanoids and have been …

Mutual two-way interactions of curcumin and gut microbiota

R Pluta, S Januszewski, M Ułamek-Kozioł - International journal of …, 2020 - mdpi.com
Curcumin, an herbal naturally occurring polyphenol, has recently been proposed for the
treatment of neurodegenerative, neurological and cancer diseases due to its pleiotropic …

Curcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB …

ZB Zhang, DD Luo, JH Xie, YF Xian, ZQ Lai… - Frontiers in …, 2018 - frontiersin.org
Curcumin (CUR), a promising naturally occurring dietary compound, is commonly
recognized as the potential anti-inflammatory agent. While the application of CUR was …

The cancer chemopreventive and therapeutic potential of tetrahydrocurcumin

CS Lai, CT Ho, MH Pan - Biomolecules, 2020 - mdpi.com
In recent decades, cancer has been one of the leading causes of death worldwide. Despite
advances in understanding the molecular basis of tumorigenesis, diagnosis, and clinical …

The use of electrospun curcumin-loaded poly (L-lactic acid) fiber mats as wound dressing materials

P Pankongadisak, S Sangklin, P Chuysinuan… - Journal of Drug Delivery …, 2019 - Elsevier
Electrospun poly (l-lactic acid)(PLLA) fiber mats containing curcumin were prepared by
electrospinning. Varying amounts of as-loaded curcumin at 0.2, 0.5, and 1.0% w/w (based …