Precision run-on sequencing (PRO-seq) for microbiome transcriptomics
Bacteria respond to environmental stimuli through precise regulation of transcription
initiation and elongation. Bulk RNA sequencing primarily characterizes mature transcripts …
initiation and elongation. Bulk RNA sequencing primarily characterizes mature transcripts …
[HTML][HTML] Inference of gene networks using gene expression data with applications
CK Chen - Heliyon, 2024 - cell.com
Gene networks (GNs) use graphs to represent the interaction relationships between genes.
Large-scale GNs are often sparse and contain hub genes that interact with many other …
Large-scale GNs are often sparse and contain hub genes that interact with many other …
[HTML][HTML] Algorithm for the Reconstruction of Mathematical Frame Models of Bacterial Transcription Regulation
TN Lakhova, FV Kazantsev, AM Mukhin, NA Kolchanov… - Mathematics, 2022 - mdpi.com
Transcription regulation plays an important role in bacterial activity. The operon concept
coined by François Jacob and Jacques Monod has had a considerable effect on …
coined by François Jacob and Jacques Monod has had a considerable effect on …
Run-on sequencing reveals nascent transcriptomics of the human microbiome
Precise regulation of transcription initiation and elongation enables bacteria to control
cellular responses to environmental stimuli. RNAseq is the most common tool for measuring …
cellular responses to environmental stimuli. RNAseq is the most common tool for measuring …
[HTML][HTML] regutools: an R package for the extraction of gene regulatory networks from RegulonDB
R is an open-source statistical environment which can be easily modified to enhance its
functionality via packages. regutools is a R package available via Bioconductor. R can be …
functionality via packages. regutools is a R package available via Bioconductor. R can be …