Coordination compounds in cancer: Past, present and perspectives

F Trudu, F Amato, P Vaňhara, T Pivetta… - Journal of applied …, 2015 - Elsevier
Metal-based coordination compounds have been used throughout the history of human
medicine to treat various diseases, including cancer. Since the discovery of cisplatin in …

Metal ions influx is a double edged sword for the pathogenesis of Alzheimer's disease

P Wang, ZY Wang - Ageing Research Reviews, 2017 - Elsevier
Alzheimer's disease (AD) is a common form of dementia in aged people, which is defined by
two pathological characteristics: β-amyloid protein (Aβ) deposition and tau …

The prevalence of metal-based drugs as therapeutic or diagnostic agents: beyond platinum

D Gaynor, DM Griffith - Dalton Transactions, 2012 - pubs.rsc.org
Metal complexes and metal salts have a wide range of medicinal applications and are
extensively administered to patients or purchased over the counter as a matter of routine …

[HTML][HTML] Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressor

E Madan, R Gogna, M Bhatt, U Pati, P Kuppusamy… - Oncotarget, 2011 - ncbi.nlm.nih.gov
Abstract p53 is well known as the “guardian of the genome” for differentiated and neoplastic
cells. p53 induces cell-cycle arrest and cell death after DNA damage and thus contributes to …

Gallium (III) complexes in cancer chemotherapy

XX Peng, S Gao, JL Zhang - European Journal of Inorganic …, 2022 - Wiley Online Library
Gallium, the group 13 metal, has been found to be potentially useful in fighting against
cancers since last century. The trivalent Ga (III) shares most chemical properties except …

Advances in anticancer alkaloid-derived metallo-chemotherapeutic agents in the last decade: Mechanism of action and future prospects

MF Ansari, HY Khan, S Tabassum, F Arjmand - Pharmacology & …, 2023 - Elsevier
Metal-based complexes have occupied a pioneering niche in the treatment of many chronic
diseases, including various types of cancers. Despite the phenomenal success of cisplatin …

Novel glycosylation zinc (II)–cryptolepine complexes perturb mitophagy pathways and trigger cancer cell apoptosis and autophagy in SK-OV-3/DDP cells

Z Zhou, LQ Du, XM Huang, LG Zhu, QC Wei… - European Journal of …, 2022 - Elsevier
With the aim of shedding some light on the mechanism of action of zinc (II) complexes in
antiproliferative processes and molecular signaling pathways, three novel glycosylated zinc …

Thiosemicarbazone complexes as versatile medicinal chemistry agents: a review

EJ Siddiqui, I Azad, AR Khan, T Khan - Journal of drug delivery and …, 2019 - jddtonline.info
Objective: Thiosemicarbazones are Schiff based ligands of significant biological importance
and their biological relevance has been studied for a considerable amount of time period …

Combinatorial delivery of gallium (III) nitrate and curcumin complex-loaded hollow mesoporous silica nanoparticles for breast cancer treatment

T Mohan Viswanathan, V Krishnakumar… - Nanomaterials, 2022 - mdpi.com
The main aims in the development of a novel drug delivery vehicle is to efficiently carry
therapeutic drugs in the body's circulatory system and successfully deliver them to the …

Bioactive metal-containing nanomaterials for ferroptotic cancer therapy

W Fei, Y Zhang, Y Ye, C Li, Y Yao, M Zhang… - Journal of Materials …, 2020 - pubs.rsc.org
The clinical performance of the current cancer therapies is still far from satisfactory. The
emerging ferroptosis-driven therapy strategies reignite the hope of chemotherapy in tumor …