Pyrazole-based analogs as potential antibacterial agents against methicillin-resistance staphylococcus aureus (MRSA) and its SAR elucidation

R Verma, SK Verma, KP Rakesh, YR Girish… - European journal of …, 2021 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is becoming lethal to humanity due to
easy transmission and difficult-to-treat skin and flimsy diseases. The most threatening aspect …

[HTML][HTML] AIE-featured tetraphenylethylene nanoarchitectures in biomedical application: Bioimaging, drug delivery and disease treatment

KSS Kumar, YR Girish, M Ashrafizadeh… - Coordination Chemistry …, 2021 - Elsevier
The development of aggregation-induced emission (AIE) has received extreme
considerations from basic and clinical researches. To date, various luminogens with AIE …

Heterogeneous graphitic carbon nitrides in visible-light-initiated organic transformations

SK Verma, R Verma, YR Girish, F Xue, L Yan… - Green …, 2022 - pubs.rsc.org
In recent years, g-C3N4 photocatalyst-mediated organic reactions have represented an
important mode of chemical transformations and are expected to become a crucial field at …

Benzimidazole analogues as efficient arsenals in war against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies

GF Zha, HD Preetham, S Rangappa, KSS Kumar… - Bioorganic …, 2021 - Elsevier
Small molecule based inhibitors development is a growing field in medicinal chemistry. In
recent years, different heterocyclic derivatives have been designed to counter the infections …

Structure-activity relationship studies of thiazole agents with potential anti methicillin-resistance Staphylococcus aureus (MRSA) activity

J Wang, S Long, Z Liu, KP Rakesh, R Verma… - Process …, 2023 - Elsevier
Due to the increasing resistance of methicillin-resistant Staphylococcus aureus (MRSA) to
conventional antibiotics, further efforts are needed to develop new antimicrobial agents …

Fluorinated azoles as effective weapons in fight against methicillin-resistance staphylococcus aureus (MRSA) and its SAR studies

SK Verma, R Verma, MB Sridhara, KSS Kumar - Bioorganic Chemistry, 2023 - Elsevier
The rapid spread of Methicillin-resistant Staphylococcus aureus (MRSA) and its difficult-to-
treat skin and filmsy diseases are making MRSA a threat to human life. The most dangerous …

Nano-ZrO2-Catalyzed Biginelli Reaction and the Synthesis of Bioactive Dihydropyrimidinones That Targets PPAR-γ in Human Breast Cancer Cells

SN Deveshegowda, JR Yang, Z Xi, O Nagaraja… - Catalysts, 2023 - mdpi.com
Bioactive dihydropyrimidinones (DHPs) were designed and synthesized by a
multicomponent Biginelli reaction. The reaction was catalyzed by the polarized surface of …

Alternative Approach to Access 5-Hydroxy-1H-pyrrol-2-(5H)-ones from Base-Induced Tandem Intramolecular Cyclization of Sulfur Ylide with Ketones and 1, 3-Hydroxy …

HD Preetham, KS Sharath Kumar, A Kandaswamy… - ACS …, 2023 - ACS Publications
An easily adaptable protocol for the preparation of 5-hydroxy-1H-pyrrol-2 (5H)-ones from
readily available starting materials has been reported. The reaction of sulfur ylides with …

Two-dimensional Ti3C2Tx MXenes as a catalyst support for the synthesis of 1, 4-disubstituted-1, 2, 3-triazoles via azide-nitroalkene oxidative cycloaddition

SK Verma, R Verma, YR Girish, S Verma… - Journal of Molecular …, 2023 - Elsevier
Two-dimensional transition metal carbides/nitrides: MXenes have become a prime choice
for researchers to exploit their outstanding properties for various applications in different …

A trisubstituted pyrazole derivative reduces DMBA-induced mammary tumor growth in rats by inhibiting estrogen receptor-α expression

H Ananda, KS Sharath Kumar, MS Sudhanva… - Molecular and cellular …, 2018 - Springer
Aberrant expression of estrogen receptor alpha (ER-α) is observed in many pathological
complications like breast cancer, endometrial cancer, and in osteoporosis. ER-α plays a vital …