Antiplasmodial natural products: an update

N Tajuddeen, FR Van Heerden - Malaria journal, 2019 - Springer
Background Malaria remains a significant public health challenge in regions of the world
where it is endemic. An unprecedented decline in malaria incidences was recorded during …

[HTML][HTML] Potential antimalarials from Nigerian plants: a review

JO Adebayo, AU Krettli - Journal of ethnopharmacology, 2011 - Elsevier
Malaria, caused by parasites of the genus Plasmodium, is one of the leading infectious
diseases in many tropical regions, including Nigeria, a West African country where …

Nanotechnology applied to the treatment of malaria

NS Santos-Magalhães, VCF Mosqueira - Advanced drug delivery reviews, 2010 - Elsevier
Despite the fact that we live in an era of advanced technology and innovation, infectious
diseases, like malaria, continue to be one of the greatest health challenges worldwide. The …

Plant-derived antimalarial agents: new leads and efficient phythomedicines. Part I. Alkaloids

AB Oliveira, MF Dolabela, FC Braga… - Anais da Academia …, 2009 - SciELO Brasil
Malaria remains one of the most serious world health problem and the major cause of
mortality and morbidity in the endemic regions. Brazil is among the 30 high-burden countries …

Ananas comosus (L) Merrill (pineapple) fruit peel extract demonstrates antimalarial, anti-nociceptive and anti-inflammatory activities in experimental models

AM Ajayi, AI Coker, OT Oyebanjo, IM Adebanjo… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacology relevance Pineapple (Ananas comosus) peel is a major waste
in pineapple canning industry and it is reported to be used in ethnomedicine as a …

Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies

J Penna-Coutinho, WA Cortopassi, AA Oliveira… - PloS one, 2011 - journals.plos.org
The Plasmodium falciparum lactate dehydrogenase enzyme (Pf LDH) has been considered
as a potential molecular target for antimalarials due to this parasite's dependence on …

Antiplasmodial natural products

CR Nogueira, LMX Lopes - Molecules, 2011 - mdpi.com
Malaria is a human infectious disease that is caused by four species of Plasmodium. It is
responsible for more than 1 million deaths per year. Natural products contain a great variety …

Evaluation of the anti-malarial activity of crude extract and solvent fractions of the leaves of Olea europaea (Oleaceae) in mice

D Misganaw, E Engidawork, T Nedi - BMC Complementary and …, 2019 - Springer
Background Drug resistance poses a challenge to malaria control measures. This calls for
discovery & development of new chemotherapeutic agents. This study therefore was …

Anti-malarial activity of the root extract of Euphorbia abyssinica (Euphorbiaceae) against Plasmodium berghei infection in mice

AB Muluye, AG Desta, SK Abate, GT Dano - Malaria Journal, 2019 - Springer
Background More than 200 medicinal plants including Euphorbia abyssinica are utilized for
treatment of malaria in Ethiopian traditional medical practices. However, the safety, efficacy …

New approaches in antimalarial drug discovery and development: a review

ACC Aguiar, EMM da Rocha, NB de Souza… - Memorias do Instituto …, 2012 - SciELO Brasil
Malaria remains a major world health problem following the emergence and spread of
Plasmodium falciparum that is resistant to the majority of antimalarial drugs. This problem …