Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review
M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …
due to the special problems they have faced, such as their increasing diversity and …
Recent advances in the anticancer applications of benzimidazole derivatives
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
Piperazin incorporated Schiff Base derivatives: Assessment of in vitro biological activities, metabolic enzyme inhibition properties, and molecular docking calculations
The cytotoxic activities of the compounds were determined by the 3‐(4, 5‐dimethylthiazolyl‐
2)‐2, 5‐diphenyltetrazolium bromide (MTT) method in human breast cancer (MCF‐7) …
2)‐2, 5‐diphenyltetrazolium bromide (MTT) method in human breast cancer (MCF‐7) …
Synthesis, biological evaluation, and molecular docking of new benzimidazole-1, 2, 3-triazole hybrids as antibacterial and antitumor agents
S Ahmed Saleh Alzahrani, S Nazreen… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A new series of benzimidazole-1, 2, 3-triazole hybrids have been successfully accomplished
by the Click chemistry of different aromatic azides and propargylated benzimidazole (4). The …
by the Click chemistry of different aromatic azides and propargylated benzimidazole (4). The …
New natural Eugenol derivatives as antiproliferative agents: synthesis, biological evaluation, and computational studies
Semisynthetic modifications of natural products have bestowed us with many anticancer
drugs. In the present work, a natural product, eugenol, has been modified synthetically to …
drugs. In the present work, a natural product, eugenol, has been modified synthetically to …
Cell cycle arrest and apoptosis-inducing ability of benzimidazole derivatives: design, synthesis, docking, and biological evaluation
S Nazreen, ASA Almalki, SEI Elbehairi, AA Shati… - Molecules, 2022 - mdpi.com
In the current study, new benzimidazole-based 1, 3, 4-oxadiazole derivatives have been
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …
Designing strategies, structural activity relationship and biological activity of recently developed nitrogen containing heterocyclic compounds as epidermal growth …
Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …
unchecked production of definite molecules. These molecules are involved in the cell growth …
In-silico design, pharmacophore-based screening, and molecular docking studies reveal that benzimidazole-1,2,3-triazole hybrids as novel EGFR inhibitors targeting …
Lung cancer is a complex and heterogeneous disease, which has been associated with
various molecular alterations, including the overexpression and mutations of the epidermal …
various molecular alterations, including the overexpression and mutations of the epidermal …
Exploring Antimicrobial Features for New Imidazo [4, 5-b] pyridine Derivatives Based on Experimental and Theoretical Study
M Hjouji, AM Almehdi, H Elmsellem, Y Seqqat… - Molecules, 2023 - mdpi.com
5-bromopyridine-2, 3-diamine reacted with benzaldehyde to afford the corresponding 6-
Bromo-2-phenyl-3H-imidazo [4, 5-b] pyridine (1). The reaction of the latter compound (1) …
Bromo-2-phenyl-3H-imidazo [4, 5-b] pyridine (1). The reaction of the latter compound (1) …
Design, synthesis, anticancer activity and molecular docking studies of new benzimidazole derivatives bearing 1, 3, 4-oxadiazole moieties as potential thymidylate …
ASA Almalki, S Nazreen, SEI Elbehairi… - New Journal of …, 2022 - pubs.rsc.org
The present work describes the synthesis and anticancer activity of new benzimidazole
derivatives bearing 1, 3, 4-oxadiazoles as thymidylate synthase inhibitors. The newly …
derivatives bearing 1, 3, 4-oxadiazoles as thymidylate synthase inhibitors. The newly …