Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

The gastrointestinal (GI) tract is a highly complex organ composed of the intestinal
epithelium layer, intestinal microbiota, and local immune system. Intestinal microbiota …

Short-chain fatty acids (SCFAs) are the main metabolites produced by the gut microbiota via
the fermentation of complex carbohydrates and fibers. Evidence suggests that SCFAs play a …

Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …

Pancreatic adenocarcinoma is one of the most lethal cancers in both men and women, with
a median five-year survival of around 5%. Therefore, pancreatic adenocarcinoma represents …

The annual incidence of Lyme disease, caused by tick-transmitted Borreliella burgdorferi, is
estimated to be at least 476,000 cases in the United States and many more worldwide. Ten …

Short-chain fatty acids (SCFAs) are a product of intestinal bacteria metabolism. Our previous
study has found that intestinal bacteria in patients with Alzheimer's disease (AD) can …

Simple Summary Pancreatic cancer is a highly lethal cancer and less than 10% of patients
survive the 5-year mark. The molecular and biological underpinnings leading to this dismal …

Sepsis is a complex clinical disorder with heterogeneous etiological factors. Given its high
mortality rate, it is considered a global health issue. Recently, the link between gut …

ABSTRACT The Lyme disease spirochete, Borrelia burgdorferi, persists in nature by
alternatingly cycling between ticks and vertebrates. During each stage of the infectious …