The aryl hydrocarbon receptor (AhR), for many years almost exclusively studied by the
pharmacology/toxicology field for its role in mediating the toxicity of xenobiotics such as 2, 3 …

The process of wound healing involves a complex and vast interplay of growth factors and
cytokines that coordinate the recruitment and interaction of various cell types. A series of …

Chronic wounds have become an economic, social, and public health burden and need
advanced treatment. Platelet-rich plasma (PRP) has been used extensively in treatment of …

Activation of the KEAP1-NRF2 signaling pathway is an adaptive response to environmental
and endogenous stresses and serves to render animals resistant to chemical …

Among other functions, the skin serves as the barrier against the environment and provides
vital protection from physical or chemical harm and from infection. Skin cells express the aryl …

While wound therapy remains a clinical challenge in current medical practice, much effort
has focused on developing biological therapeutic approaches. This paper presents a …

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates
the biological and toxic effects of its xenobiotic ligands. Previous cell culture studies have …

The skin is constantly exposed to a variety of environmental threats, including solar
electromagnetic radiation, microbes, airborne particulate matter, and chemicals. Acute …

An immunoregulatory role of aryl hydrocarbon receptor (AhR) has been shown in
conventional αβ and γδ T cells, but its function in skin γδ T cells (dendritic epidermal T cells …

The aryl hydrocarbon receptor (AhR) recognizes a large number of xenobiotics, such as
polyaromatic hydrocarbons (PAHs) and dioxins, and it activates several metabolic and …