Traditional Chinese Medicine has great potential as candidate drugs for lung cancer: A review

Z Wei, J Chen, F Zuo, J Guo, X Sun, D Liu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance With high mortality and morbidity rates, lung cancer (LC)
has become one of the major threats to human health. The treatment strategies for LC …

[HTML][HTML] Pre-clinical and clinical importance of miR-21 in human cancers: Tumorigenesis, therapy response, delivery approaches and targeting agents

M Hashemi, MSA Mirdamadi, Y Talebi… - Pharmacological …, 2023 - Elsevier
The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …

[HTML][HTML] Natural products, alone or in combination with FDA-approved drugs, to treat COVID-19 and lung cancer

L Yang, Z Wang - Biomedicines, 2021 - mdpi.com
As a public health emergency of international concern, the highly contagious coronavirus
disease 2019 (COVID-19) pandemic has been identified as a severe threat to the lives of …

[HTML][HTML] Recent insights into the microRNA-dependent modulation of gliomas from pathogenesis to diagnosis and treatment

A Mafi, A Rahmati, Z Babaei Aghdam, R Salami… - Cellular & Molecular …, 2022 - Springer
Gliomas are the most lethal primary brain tumors in adults. These highly invasive tumors
have poor 5-year survival for patients. Gliomas are principally characterized by rapid …

[HTML][HTML] Small in size, but large in action: microRNAs as potential modulators of PTEN in breast and lung cancers

AJ Abadi, A Zarrabi, MH Gholami, S Mirzaei… - Biomolecules, 2021 - mdpi.com
MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

[HTML][HTML] Sinomenine ameliorates adjuvant-induced arthritis by inhibiting the autophagy/NETosis/inflammation axis

H Jiang, Q Lu, J Xu, G Huo, Y Cai, S Geng, H Xu… - Scientific Reports, 2023 - nature.com
Studies have found that neutrophil extracellular traps (NETs) which are the specific dying
form of neutrophil upon activation have fundamental role in the rheumatoid arthritis onset …

From mundane to classic: Sinomenine as a multi‐therapeutic agent

D Li, Z Zhong, CN Ko, T Tian… - British Journal of …, 2023 - Wiley Online Library
Sinomenine is an active substance extracted from the traditional Chinese medicine
Sinomenium acutum. Sinomenine has been shown to mediate a wide range of …

[HTML][HTML] Recent advancements in drug delivery of sinomenine, A disease-modifying anti-rheumatic drug

X Chen, C Lu, Y Duan, Y Huang - Pharmaceutics, 2022 - mdpi.com
Sinomenine (SIN) is a benzyltetrahydroisoquinoline-type alkaloid isolated from the dried
plant root and stem of Sinomenium acutum (Thumb.) Rehd. et Wils, which shows potent anti …

[HTML][HTML] Synthetic miR-21 decoy circularized by tRNA splicing mechanism inhibited tumorigenesis in glioblastoma in vitro and in vivo models

H Bayat, MH Pourgholami, S Rahmani… - … Therapy-Nucleic Acids, 2023 - cell.com
Glioblastoma multiforme (GBM) is the deadliest primary central nervous system tumor.
miRNAs (miRs), a class of non-coding RNAs, are considered pivotal post-transcriptional …

A review on pharmacokinetics of sinomenine and its anti-inflammatory and immunomodulatory effects

S Wang, L Zhang, Y Zhou, Z Liu, Z Zhou… - International …, 2023 - Elsevier
Autoimmune diseases (ADs), with significant effects on morbidity and mortality, are a broad
spectrum of disorders featured by body's immune responses being directed against its own …