[HTML][HTML] Relieving metabolic burden to improve robustness and bioproduction by industrial microorganisms
Metabolic burden is defined by the influence of genetic manipulation and environmental
perturbations on the distribution of cellular resources. The rewiring of microbial metabolism …
perturbations on the distribution of cellular resources. The rewiring of microbial metabolism …
[HTML][HTML] New synthetic biology tools for metabolic control
In industrial bioprocesses, microbial metabolism dictates the product yields, and therefore,
our capacity to control it has an enormous potential to help us move towards a bio-based …
our capacity to control it has an enormous potential to help us move towards a bio-based …
Light-driven CO2 sequestration in Escherichia coli to achieve theoretical yield of chemicals
CO2 sequestration engineering is an attractive strategy for achieving carbon-and energy-
efficient bioproduction. However, the efficiency of heterotrophic CO2 sequestration is limited …
efficient bioproduction. However, the efficiency of heterotrophic CO2 sequestration is limited …
Living intracellular inorganic-microorganism biohybrid system for efficient solar hydrogen generation
D Wu, W Zhang, B Fu, Z Zhang - Joule, 2022 - cell.com
The thirsty demand for renewable, sustainable, and efficient hydrogen production has
promoted the rapid development of advanced technologies, and whole-cell microorganism …
promoted the rapid development of advanced technologies, and whole-cell microorganism …
Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli
Genetically programmed circuits allowing bifunctional dynamic regulation of enzyme
expression have far-reaching significances for various bio-manufactural purposes. However …
expression have far-reaching significances for various bio-manufactural purposes. However …
Engineering AraC to make it responsive to light instead of arabinose
E Romano, A Baumschlager, EB Akmeric… - Nature chemical …, 2021 - nature.com
The l-arabinose-responsive AraC and its cognate PBAD promoter underlie one of the most
often used chemically inducible prokaryotic gene expression systems in microbiology and …
often used chemically inducible prokaryotic gene expression systems in microbiology and …
Enhancing biofuels production by engineering the actin cytoskeleton in Saccharomyces cerevisiae
H Liu, P Zhou, M Qi, L Guo, C Gao, G Hu… - Nature …, 2022 - nature.com
Saccharomyces cerevisiae is widely employed as a cell factory for the production of biofuels.
However, product toxicity has hindered improvements in biofuel production. Here, we …
However, product toxicity has hindered improvements in biofuel production. Here, we …
Light-regulated gene expression in Bacteria: Fundamentals, advances, and perspectives
R Ohlendorf, A Möglich - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Numerous photoreceptors and genetic circuits emerged over the past two decades and now
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …
The promise of optogenetics for bioproduction: dynamic control strategies and scale-up instruments
Progress in metabolic engineering and synthetic and systems biology has made
bioproduction an increasingly attractive and competitive strategy for synthesizing …
bioproduction an increasingly attractive and competitive strategy for synthesizing …
Optogenetics in bacteria–applications and opportunities
Optogenetics holds the promise of controlling biological processes with superb temporal
and spatial resolution at minimal perturbation. Although many of the light-reactive proteins …
and spatial resolution at minimal perturbation. Although many of the light-reactive proteins …