Nitric oxide (NO), a free radical, plays a critical role in a wide range of physiological and
pathological processes. Due to its pleiotropic function, it has been widely investigated in …

RRx-001 is a shape shifting small molecule with Fast Track designation for the prevention/
amelioration of chemoradiation-induced severe oral mucositis (SOM) in newly diagnosed …

Carbon quantum dots (CQDs) are extensively applied for bioimaging due to their unique
photoluminescence properties, while less attention has been paid to their inherent bio …

Background: Hydrogen sulfide is a critical endogenous signaling molecule that exerts
protective effects in the setting of heart failure. Cystathionine γ-lyase (CSE), 1 of 3 hydrogen …

Background Long‐term feeding with a high‐fat diet (HFD) induces endothelial dysfunction in
mice, but early HFD‐induced effects on endothelium have not been well characterized …

Nitric oxide, carbon monoxide and hydrogen sulfide are three endogenous gasotransmitters
that serve a role in regulating normal and pathological cellular activities. They can stimulate …

In the last decade, immune therapies against human cancers have emerged as a very
effective therapeutic strategy in the treatment of various cancers, some of which are resistant …

Background: NOS3 (endothelial NOS, eNOS) is a member of the nitric oxide synthase (NOS)
enzyme family, mainly participating in nitric oxide (NO) generation. NOS3 has been reported …

Background The early detection of metastasis based on biomarkers in plasma may improve
cancer prognosis and guide treatment. The aim of this work was to characterize alterations …

Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease (ILD) sharing various
genetic, molecular and cell processes with lung cancer (LC). Nintedanib, a tyrosine-kinase …