Levothyroxine (l-thyroxine, l-T4) is a drug of choice for treating congenital and primary
hypothyroidism. Although clinically significant interactions between l-T4 and food can alter …

Although levothyroxine is one of the most prescribed medications in the world, its
bioavailability has been reported to be impaired by many factors, including interfering drugs …

Autoimmune thyroid diseases (AITD) are T-cell-mediated organ specific autoimmune
disorders, deriving from an altered response of the immune system that leads to the immune …

Oral levothyroxine sodium is absorbed in the small intestine, mainly in the jejunum and the
ileum being lower the absorption rate at duodenal level. The time interval between the …

Purpose In patients with hypothyroidism, levothyroxine (LT4) is the treatment of choice, and
tablets are the most commonly prescribed formulation. Despite multiple scenarios being …

Abstract In France, more than 2.5 million patients are currently treated with levothyroxine,
mainly as the marketed product Levothyrox®. In March 2017, at the request of French …

Levothyroxine (T4) is a critical-dose drug, because little variations in the blood concentration
may cause treatment failure as well as iatrogenic thyrotoxicosis. Despite the dose response …

Levothyroxine (L-T4) absorption can be impaired by various causes: a) L-T4 ingestion
during breakfast, or with food; b) conditions of reduced gastric acidity; c) intestinal …

Background: The metabolic syndrome (MetS) represents a clustering of risk factors for
cardiovascular diseases that includes abdominal obesity, hypertension, dyslipidemia, and …

Background: Levothyroxine (LT4) sodium is a standard treatment for hypothyroidism. Its
absorption and bioavailability when taken as a tablet have been shown to be significantly …