Network pharmacology provides a systematic approach to understanding the treatment of ischemic heart diseases with traditional Chinese medicine

HY Yang, ML Liu, P Luo, XS Yao, H Zhou - Phytomedicine, 2022 - Elsevier
Background The field of network pharmacology showed significant development. The
concept of network pharmacology has many similarities to the philosophy of traditional …

Systems pharmacology for investigation of the mechanisms of action of traditional Chinese medicine in drug discovery

W Zhang, Y Huai, Z Miao, A Qian… - Frontiers in pharmacology, 2019 - frontiersin.org
As a traditional medical intervention in Asia and a complementary and alternative medicine
in western countries, traditional Chinese medicine (TCM) has attracted global attention in …

[HTML][HTML] Mechanisms underlying the therapeutic effects of Qingfeiyin in treating acute lung injury based on GEO datasets, network pharmacology and molecular …

Y Wang, Y Yuan, W Wang, Y He, H Zhong… - Computers in biology …, 2022 - Elsevier
Background Qingfeiyin (QFY) is a common Chinese herbal formula for the treatment of acute
lung injury (ALI). However, its mechanisms of action are unclear. In this study, we …

Chemical characterization and gastroprotective effect of an isolated polysaccharide fraction from Bletilla striata against ethanol-induced acute gastric ulcer

C Zhang, F Gao, S Gan, Y He, Z Chen, X Liu… - Food and chemical …, 2019 - Elsevier
The chemical characterization and protective role against ethanol-induced gastric ulcerated
rats of a polysaccharide fraction from Bletilla striata (BSP) collected by ultrafiltration …

Mechanisms of indigo naturalis on treating ulcerative colitis explored by GEO gene chips combined with network pharmacology and molecular docking

S Gu, Y Xue, Y Gao, S Shen, Y Zhang, K Chen, S Xue… - Scientific reports, 2020 - nature.com
Oral administration of indigo naturalis (IN) can induce remission in ulcerative colitis (UC);
however, the underlying mechanism remains unknown. The main active components and …

Network pharmacology exploration reveals endothelial inflammation as a common mechanism for stroke and coronary artery disease treatment of Danhong injection

M Lyu, CL Yan, HX Liu, TY Wang, XH Shi, JP Liu… - Scientific Reports, 2017 - nature.com
Although Danhong injection (DHI) is the most widely prescribed Chinese medicine for both
stroke and coronary artery disease (CAD), its underlying common molecular mechanisms …

Acupuncture and neural mechanism in the management of low back pain—an update

TK Lim, Y Ma, F Berger, G Litscher - Medicines, 2018 - mdpi.com
Within the last 10 years, the percentage of low back pain (LBP) prevalence increased by
18%. The management and high cost of LBP put a tremendous burden on the healthcare …

Gastroprotective Effects of Ganoderma lucidum Polysaccharides with Different Molecular Weights on Ethanol-Induced Acute Gastric Injury in Rats

B Tian, Q Zhao, H Xing, J Xu, Z Li, H Zhu, K Yang… - Nutrients, 2022 - mdpi.com
Ganoderma lucidum is known as a medicine food homology that can ameliorate
gastrointestinal diseases. To evaluate the gastroprotective effects on different Ganoderma …

Systematic elucidation of the mechanism of geraniol via network pharmacology

YF Zhang, Y Huang, YH Ni, ZM Xu - Drug design, development and …, 2019 - Taylor & Francis
Background Geraniol is an acyclic monoterpene alcohol, which is extracted from the
ethereal oils of aromatic plants. A systematic analysis of its mechanism of action has not yet …

[HTML][HTML] The atherosclerosis-ameliorating effects and molecular mechanisms of BuYangHuanWu decoction

B Liu, Z Song, J Yu, P Li, Y Tang, J Ge - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Atherosclerosis (AS) is one of the leading causes of cardiovascular disease and has a high
rate of morbidity and mortality. Traditional Chinese Medicine (TCM) supplied many therapies …