Several studies suggest that topographical patterns influence nerve cell fate. Efforts have
been made to improve nerve cell functionality through this approach, focusing on …

Peripheral nerve injuries present significant challenges in regenerative medicine, primarily
due to inherent limitations in the body's natural healing processes. In response to these …

Peripheral nerve injury is a common clinical disease. Effective post-injury nerve repair
remains a challenge in neurosurgery, and clinical outcomes are often unsatisfactory …

Nerve conduits may represent a valuable alternative to autograft for the regeneration of long-
gap damages. However, no NCs have currently reached market approval for the …

Melt electrowriting (MEW) is an innovative technique for fabricating 3D porous materials or
scaffolds with microscale architectures. However, the multitude of printing parameters makes …

Large-gap nerve defects require nerve guide conduits (NGCs) for complete regeneration
and muscle innervation. Many NGCs have been developed using various scaffold designs …

Critical-sized peripheral nerve injuries pose a significant clinical challenge and lead to
functional loss and disability. Current regeneration strategies, including autografts, synthetic …

Extracellular vesicles from skin-derived precursor Schwann cells (SKP-SC-EVs) promote
neurite outgrowth in culture and enhance peripheral nerve regeneration in rats. This study …

Peripheral nervous system (PNS) injuries often lead to significant sensory and motor
impairments. Traditional artificial nerve conduits, lacking anisotropic structures, have been …

Advanced artificial nerve conduits offer a promising alternative for nerve injury repair.
Current research focuses on improving the therapeutic effectiveness of nerve conduits by …