The field guide to 3D printing in optical microscopy for life sciences

M Del Rosario, HS Heil, A Mendes… - Advanced …, 2022 - Wiley Online Library
The maker movement has reached the optics labs, empowering researchers to create and
modify microscope designs and imaging accessories. 3D printing has a disruptive impact on …

A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer

S Coppola, I Carnevale, EHJ Danen, GJ Peters… - Drug Resistance …, 2017 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a highly chemoresistant malignancy. This
chemoresistant phenotype has been historically associated with genetic factors. Major …

An ultra-fast mechanically active cell culture substrate

A Poulin, M Imboden, F Sorba, S Grazioli… - Scientific reports, 2018 - nature.com
We present a mechanically active cell culture substrate that produces complex strain
patterns and generates extremely high strain rates. The transparent miniaturized cell …

Uniaxial Cyclic Cell Stretching Device for Accelerating Cellular Studies

S Yadav, P Singha, NK Nguyen, CH Ooi… - Micromachines, 2023 - mdpi.com
Cellular response to mechanical stimuli is a crucial factor for maintaining cell homeostasis.
The interaction between the extracellular matrix and mechanical stress plays a significant …

The CaT stretcher: An open-source system for delivering uniaxial strain to cells and tissues (CaT)

Y Wang, R Singer, X Liu, SJ Inman, Q Cao… - … in Bioengineering and …, 2022 - frontiersin.org
Integration of mechanical cues in conventional 2D or 3D cell culture platforms is an
important consideration for in vivo and ex vivo models of lung health and disease. Available …

Design, implementation, and validation of a piezoelectric device to study the effects of dynamic mechanical stimulation on cell proliferation, migration and morphology

D Mojena-Medina, M Martínez-Hernández… - Sensors, 2020 - mdpi.com
Cell functions and behavior are regulated not only by soluble (biochemical) signals but also
by biophysical and mechanical cues within the cells' microenvironment. Thanks to the …

Deoxynivalenol induces structural alterations in epidermoid carcinoma cells A431 and impairs the response to biomechanical stimulation

G Del Favero, L Woelflingseder, L Janker… - Scientific Reports, 2018 - nature.com
Morphology together with the capability to respond to surrounding stimuli are key elements
governing the spatial interaction of living cells with the environment. In this respect …

In vitro magnetic techniques for investigating cancer progression

S Libring, A Enriquez, H Lee, L Solorio - Cancers, 2021 - mdpi.com
Simple Summary This review focuses on the advantages achieved by incorporating
magnetic forces into culture platforms used to study cancer progression in the laboratory …

Development and validation of a device for in vitro uniaxial cell substrate deformation with real-time strain control

L Apa, S Carraro, S Pisu, B Peruzzi… - Measurement …, 2020 - iopscience.iop.org
Substrate deformation affects the behaviour of many cell types, including bone, skeletal
muscle and endothelial cells. Nowadays, in vitro tests are widely employed to study the …

A perspective on developing modeling and image analysis tools to investigate mechanosensing proteins

S Ouderkirk, A Sedley, M Ong… - Integrative and …, 2023 - academic.oup.com
The shift of funding organizations to prioritize interdisciplinary work points to the need for
workflow models that better accommodate interdisciplinary studies. Most scientists are …