The field guide to 3D printing in optical microscopy for life sciences
The maker movement has reached the optics labs, empowering researchers to create and
modify microscope designs and imaging accessories. 3D printing has a disruptive impact on …
modify microscope designs and imaging accessories. 3D printing has a disruptive impact on …
A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer
S Coppola, I Carnevale, EHJ Danen, GJ Peters… - Drug Resistance …, 2017 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a highly chemoresistant malignancy. This
chemoresistant phenotype has been historically associated with genetic factors. Major …
chemoresistant phenotype has been historically associated with genetic factors. Major …
An ultra-fast mechanically active cell culture substrate
We present a mechanically active cell culture substrate that produces complex strain
patterns and generates extremely high strain rates. The transparent miniaturized cell …
patterns and generates extremely high strain rates. The transparent miniaturized cell …
Uniaxial Cyclic Cell Stretching Device for Accelerating Cellular Studies
Cellular response to mechanical stimuli is a crucial factor for maintaining cell homeostasis.
The interaction between the extracellular matrix and mechanical stress plays a significant …
The interaction between the extracellular matrix and mechanical stress plays a significant …
The CaT stretcher: An open-source system for delivering uniaxial strain to cells and tissues (CaT)
Y Wang, R Singer, X Liu, SJ Inman, Q Cao… - … in Bioengineering and …, 2022 - frontiersin.org
Integration of mechanical cues in conventional 2D or 3D cell culture platforms is an
important consideration for in vivo and ex vivo models of lung health and disease. Available …
important consideration for in vivo and ex vivo models of lung health and disease. Available …
Design, implementation, and validation of a piezoelectric device to study the effects of dynamic mechanical stimulation on cell proliferation, migration and morphology
D Mojena-Medina, M Martínez-Hernández… - Sensors, 2020 - mdpi.com
Cell functions and behavior are regulated not only by soluble (biochemical) signals but also
by biophysical and mechanical cues within the cells' microenvironment. Thanks to the …
by biophysical and mechanical cues within the cells' microenvironment. Thanks to the …
Deoxynivalenol induces structural alterations in epidermoid carcinoma cells A431 and impairs the response to biomechanical stimulation
G Del Favero, L Woelflingseder, L Janker… - Scientific Reports, 2018 - nature.com
Morphology together with the capability to respond to surrounding stimuli are key elements
governing the spatial interaction of living cells with the environment. In this respect …
governing the spatial interaction of living cells with the environment. In this respect …
In vitro magnetic techniques for investigating cancer progression
Simple Summary This review focuses on the advantages achieved by incorporating
magnetic forces into culture platforms used to study cancer progression in the laboratory …
magnetic forces into culture platforms used to study cancer progression in the laboratory …
Development and validation of a device for in vitro uniaxial cell substrate deformation with real-time strain control
L Apa, S Carraro, S Pisu, B Peruzzi… - Measurement …, 2020 - iopscience.iop.org
Substrate deformation affects the behaviour of many cell types, including bone, skeletal
muscle and endothelial cells. Nowadays, in vitro tests are widely employed to study the …
muscle and endothelial cells. Nowadays, in vitro tests are widely employed to study the …
A perspective on developing modeling and image analysis tools to investigate mechanosensing proteins
S Ouderkirk, A Sedley, M Ong… - Integrative and …, 2023 - academic.oup.com
The shift of funding organizations to prioritize interdisciplinary work points to the need for
workflow models that better accommodate interdisciplinary studies. Most scientists are …
workflow models that better accommodate interdisciplinary studies. Most scientists are …