Structural diversity and biological activities of novel secondary metabolites from endophytes

H Gao, G Li, HX Lou - Molecules, 2018 - mdpi.com
Exploration of structurally novel natural products greatly facilitates the discovery of
biologically active pharmacophores that are biologically validated starting points for the …

Unusual secondary metabolites from the mangrove ecosystems: Structures, bioactivities, chemical, and bio-syntheses

MJ Wu, B Xu, YW Guo - Marine Drugs, 2022 - mdpi.com
Mangrove ecosystems are widely distributed in the intertidal zone of tropical and subtropical
estuaries or coasts, containing abundant biological communities, for example, mangrove …

Blue Light Irradiated Metal-, Oxidant-, and Base-Free Cross-Dehydrogenative Coupling of C(sp2)–H and N–H Bonds: Amination of Naphthoquinones with Amines

RK Jha, M Batabyal, S Kumar - The Journal of Organic Chemistry, 2023 - ACS Publications
Herein, we report a blue-light-driven amination of C (sp 2)–H bond of naphthoquinones and
quinones with the N–H bond of primary and secondary amines for the synthesis of 2-amino …

Synthesis of Bioactive 3,4-Dihydro-2H-naphtho[2,3-b][1,4]oxazine-5,10-dione and 2,3,4,5-Tetrahydro-1H-naphtho[2,3-b]azepine-6,11-dione Derivatives via the …

H You, SR Vegi, C Lagishetti, S Chen… - The Journal of …, 2018 - ACS Publications
A convenient synthesis of 3, 4-dihydro-2 H-naphtho [2, 3-b][1, 4] oxazine-5, 10-diones and 2,
3, 4, 5-tetrahydro-1 H-naphtho [2, 3-b] azepine-6, 11-diones via the copper-catalyzed …

Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine‐2, 3‐dioxygenase (IDO) as Potential Target for …

CE Blunt, C Torcuk, Y Liu, W Lewis… - Angewandte Chemie …, 2015 - Wiley Online Library
Natural quinones, often linked with cellular oxidation processes, exhibit pronounced
biological activity. In particular, the structurally unique isothiazolonaphthoquinone …

Seven-membered rings

JH Ryan, JA Smith, C Hyland, AG Meyer… - Progress in Heterocyclic …, 2014 - Elsevier
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Recent applications of Birch reduction in total synthesis of natural products

MM Heravi, MV Fard, Z Faghihi - Current Organic Chemistry, 2015 - ingentaconnect.com
The Birch reduction is unique, in synthetic approaches, due to the adaptable substitution
patterns of the substituted cyclohexa-1, 4-and 1, 3-dienes, particularly enol ethers. Birch …

[PDF][PDF] 1, 3-Dipolar cycloaddition reactions of azomethine ylides with aromatic dipolarophiles

JH Ryan - Arkivoc, 2015 - arkat-usa.org
Abstract The 1, 3-dipolar cycloadditions of azomethine ylides to aromatic dipolarophiles are
reviewed and discussed. The reaction proceeds with stabilized and non-stabilized …

Genome mining of Streptomyces olivaceus SCSIO T05: Discovery of olimycins A and B and assignment of absolute configurations

C Sun, C Zhang, X Qin, X Wei, Q Liu, Q Li, J Ju - Tetrahedron, 2018 - Elsevier
Naphthoquinone macrolides have attracted considerable synthetic interest due to their
unique scaffolds, but there was no completion of total synthesis reported. In this study …

Divergolide congeners illuminate alternative reaction channels for ansamycin diversification

L Ding, J Franke, C Hertweck - Organic & Biomolecular Chemistry, 2015 - pubs.rsc.org
Isolation and structure elucidation of six new divergolides reveal unusual ansamycin
diversification reactions including formation of the unusual isobutenyl side chain from a …