Intrarenal autoregulatory mechanisms maintain renal blood flow (RBF) and glomerular
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …

Endothelin (ET) peptides and their receptors are intimately involved in the physiological
control of systemic blood pressure and body Na homeostasis, exerting these effects through …

Tumor‐targeted photodynamic therapy (PDT) is desirable as it can achieve efficient killing of
tumor cells with no or less harm to normal cells. Herein, a facile molecular engineering …

The protease renin is the key enzyme of the renin-angiotensin-aldosterone cascade, which
is relevant under both physiological and pathophysiological settings. The kidney is the only …

Large-conductance potassium (BK) channels in vascular smooth muscle cells (VSMCs)
sense both changes in membrane potential and in intracellular Ca2+ concentration. BK …

Perfusion of the renal medulla plays an important role in salt and water balance. Pericytes
are smooth muscle-like cells that impart contractile function to descending vasa recta (DVR) …

The kidney displays highly efficient autoregulation so that under steady-state conditions
renal blood flow (RBF) is independent of blood pressure over a wide range of pressure …

The distribution of voltage-dependent calcium channels in kidney pre-and postglomerular
resistance vessels was determined at the molecular and functional levels. Reverse …

Since its discovery in 1988 as an endothelial cell-derived peptide that exerts the most potent
vasoconstriction of any known endogenous compound, endothelin (ET) has emerged as an …

Over the years, it has been discussed whether T-type calcium channels Cav3 play a role in
the cardiovascular and renal system. T-type channels have been reported to play an …